HCSGD entry for GABRA1

1. General information

Official gene symbolGABRA1
Entrez ID2554
Gene full namegamma-aminobutyric acid (GABA) A receptor, alpha 1
Other gene symbolsECA4 EJM EJM5
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004890GABA-A receptor activityIEAmolecular_function
GO:0005230Extracellular ligand-gated ion channel activityIEAmolecular_function
GO:0005254Chloride channel activityIEAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneIEA ISScellular_component
GO:0006810TransportTASbiological_process
GO:0007214Gamma-aminobutyric acid signaling pathwayIEAbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0008144Drug bindingIEA ISSmolecular_function
GO:0016021Integral component of membraneIEAcellular_component
GO:0016917GABA receptor activityISSmolecular_function
GO:0030054Cell junctionIEAcellular_component
GO:0034220Ion transmembrane transportTASbiological_process
GO:0034707Chloride channel complexIEAcellular_component
GO:0045211Postsynaptic membraneIEAcellular_component
GO:0051932Synaptic transmission, GABAergicIEA ISSbiological_process
GO:0055085Transmembrane transportTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.75123722120.88740906120.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0505713670
GSE13712_SHEARDown-0.0671473020
GSE13712_STATICUp0.0510090832
GSE19018Down-0.0249959372
GSE19899_A1Up0.0691935577
GSE19899_A2Down-0.1372154355
PubMed_21979375_A1Up0.1621895641
PubMed_21979375_A2Up0.0116513715
GSE35957Up0.1138038657
GSE36640Up0.0708852167
GSE54402Up0.0420919930
GSE9593Down-0.0734033148
GSE43922Up0.0146087008
GSE24585Down-0.0450684897
GSE37065Up0.0018167755
GSE28863_A1Up0.0695247706
GSE28863_A2Up0.0154031603
GSE28863_A3Up0.1298662730
GSE28863_A4Up0.0770581468
GSE48662Up0.0524289336

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT019183MicroarrayFunctional MTI (Weak)18185580
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.