HCSGD entry for G6PC

1. General information

Official gene symbolG6PC
Entrez ID2538
Gene full nameglucose-6-phosphatase, catalytic subunit
Other gene symbolsG6PC1 G6PT GSD1 GSD1a
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003824Catalytic activityIEAmolecular_function
GO:0004346Glucose-6-phosphatase activityIDAmolecular_function
GO:0005789Endoplasmic reticulum membraneTAScellular_component
GO:0005975Carbohydrate metabolic processTASbiological_process
GO:0005977Glycogen metabolic processTASbiological_process
GO:0005980Glycogen catabolic processIEAbiological_process
GO:0006094GluconeogenesisIEA IMPbiological_process
GO:0006641Triglyceride metabolic processIEAbiological_process
GO:0008202Steroid metabolic processIEAbiological_process
GO:0008645Hexose transportTASbiological_process
GO:0010468Regulation of gene expressionIEAbiological_process
GO:0015758Glucose transportTASbiological_process
GO:0015760Glucose-6-phosphate transportIEAbiological_process
GO:0016020MembraneIEAcellular_component
GO:0016021Integral component of membraneIDAcellular_component
GO:0016311DephosphorylationIDAbiological_process
GO:0016773Phosphotransferase activity, alcohol group as acceptorIEAmolecular_function
GO:0030176Integral component of endoplasmic reticulum membraneTAScellular_component
GO:0035264Multicellular organism growthIEAbiological_process
GO:0042301Phosphate ion bindingIMPmolecular_function
GO:0042593Glucose homeostasisIMPbiological_process
GO:0042632Cholesterol homeostasisIEAbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046415Urate metabolic processIEAbiological_process
GO:0051156Glucose 6-phosphate metabolic processIEAbiological_process
GO:0055085Transmembrane transportTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.69113774930.86183868010.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0250344861
GSE13712_SHEARDown-0.1027628449
GSE13712_STATICUp0.1876110783
GSE19018Up0.1132600248
GSE19899_A1Up0.1738660021
GSE19899_A2Down-0.0536019012
PubMed_21979375_A1Up0.0036641593
PubMed_21979375_A2Up0.0596355240
GSE35957Up0.1209124766
GSE36640Down-0.0522760756
GSE54402Down-0.0079491494
GSE9593Up0.1515125890
GSE43922Up0.0197891741
GSE24585Up0.0154313800
GSE37065Down-0.1123607569
GSE28863_A1Down-0.1156213795
GSE28863_A2Up0.0076999118
GSE28863_A3Up0.1671247502
GSE28863_A4Up0.0021961848
GSE48662Down-0.0034988138

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-23a-3pMIMAT0000078MIRT006281Luciferase reporter assayFunctional MTI22318941
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.