HCSGD entry for CERS6
1. General information
| Official gene symbol | CERS6 |
|---|---|
| Entrez ID | 253782 |
| Gene full name | ceramide synthase 6 |
| Other gene symbols | CERS5 LASS6 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0006665 | Sphingolipid metabolic process | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0030148 | Sphingolipid biosynthetic process | TAS | biological_process |
| GO:0031965 | Nuclear membrane | IEA | cellular_component |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046513 | Ceramide biosynthetic process | IEA | biological_process |
| GO:0050291 | Sphingosine N-acyltransferase activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4225644124 | 0.0234982713 | 0.9999902473 | 0.2956036772 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3246360204 |
| GSE13712_SHEAR | Up | 0.0558432830 |
| GSE13712_STATIC | Up | 0.4388057661 |
| GSE19018 | Down | -0.3714020877 |
| GSE19899_A1 | Down | -0.0441040545 |
| GSE19899_A2 | Down | -1.6523142464 |
| PubMed_21979375_A1 | Down | -1.1136452346 |
| PubMed_21979375_A2 | Down | -0.6828232369 |
| GSE35957 | Up | 0.4612359750 |
| GSE36640 | Down | -3.4692804497 |
| GSE54402 | Down | -1.1447348126 |
| GSE9593 | Up | 0.5352420263 |
| GSE43922 | Down | -0.7175478286 |
| GSE24585 | Up | 0.1417483333 |
| GSE37065 | Down | -0.1319567566 |
| GSE28863_A1 | Down | -0.0717714569 |
| GSE28863_A2 | Up | 0.5384838048 |
| GSE28863_A3 | Down | -0.0567569327 |
| GSE28863_A4 | Up | 0.0786370498 |
| GSE48662 | Up | 0.3265837758 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-192-5p | MIMAT0000222 | MIRT026363 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030725 | Microarray | Functional MTI (Weak) | 18591254 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
