HCSGD entry for FAM21C


1. General information

Official gene symbolFAM21C
Entrez ID253725
Gene full namefamily with sequence similarity 21, member C
Other gene symbolsFAM21A VPEF
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005768EndosomeIDAcellular_component
GO:0005769Early endosomeIDAcellular_component
GO:0005886Plasma membraneIEAcellular_component
GO:0031901Early endosome membraneIEAcellular_component
GO:0042147Retrograde transport, endosome to GolgiIMPbiological_process
GO:0071203WASH complexIDA IEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.02654018840.98157672200.37986095701.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.7970831849
GSE13712_SHEARDown-0.1184250602
GSE13712_STATICUp0.2441582076
GSE19018Down-0.2695822178
GSE19899_A1Up0.1082701121
GSE19899_A2Up0.5562917191
PubMed_21979375_A1Up0.4089994503
PubMed_21979375_A2Up1.1059190529
GSE35957Down-0.1383246437
GSE36640Up0.2856953749
GSE54402Up0.1777994146
GSE9593Up0.6079861295
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1Up0.1869161387
GSE28863_A2Up0.0711615561
GSE28863_A3Down-0.0423026389
GSE28863_A4Up0.0826003588
GSE48662Up0.5430299112

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-598-3pMIMAT0003266MIRT040482CLASHFunctional MTI (Weak)23622248
hsa-miR-149-5pMIMAT0000450MIRT045583CLASHFunctional MTI (Weak)23622248
hsa-miR-27a-3pMIMAT0000084MIRT050034CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.