HCSGD entry for ADAM2
1. General information
| Official gene symbol | ADAM2 |
|---|---|
| Entrez ID | 2515 |
| Gene full name | ADAM metallopeptidase domain 2 |
| Other gene symbols | CRYN1 CRYN2 CT15 FTNB PH-30b PH30 PH30-beta |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004222 | Metalloendopeptidase activity | IEA | molecular_function |
| GO:0005178 | Integrin binding | TAS | molecular_function |
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0007155 | Cell adhesion | IEA | biological_process |
| GO:0007229 | Integrin-mediated signaling pathway | IEA | biological_process |
| GO:0007338 | Single fertilization | TAS | biological_process |
| GO:0007339 | Binding of sperm to zona pellucida | TAS | biological_process |
| GO:0007342 | Fusion of sperm to egg plasma membrane | TAS | biological_process |
| GO:0008237 | Metallopeptidase activity | TAS | molecular_function |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0008542 | Visual learning | IEA | biological_process |
| GO:0009986 | Cell surface | IEA | cellular_component |
| GO:0030534 | Adult behavior | IEA | biological_process |
| GO:0032504 | Multicellular organism reproduction | TAS | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9018779758 | 0.6033912579 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1468590108 |
| GSE13712_SHEAR | Down | -0.3865335622 |
| GSE13712_STATIC | Down | -0.1535526394 |
| GSE19018 | Up | 0.1565171668 |
| GSE19899_A1 | Up | 0.0178311133 |
| GSE19899_A2 | Up | 0.0329724972 |
| PubMed_21979375_A1 | Up | 0.1151468971 |
| PubMed_21979375_A2 | Down | -0.0930865395 |
| GSE35957 | Up | 0.0345947044 |
| GSE36640 | Up | 0.2039258438 |
| GSE54402 | Down | -0.0547420392 |
| GSE9593 | Down | -0.1567683938 |
| GSE43922 | Up | 0.0237052225 |
| GSE24585 | Down | -0.0980647523 |
| GSE37065 | Down | -0.0840172270 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.0256252856 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017910 | Microarray | Functional MTI (Weak) | 18185580 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
