HCSGD entry for FTL
1. General information
| Official gene symbol | FTL |
|---|---|
| Entrez ID | 2512 |
| Gene full name | ferritin, light polypeptide |
| Other gene symbols | NBIA3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005506 | Iron ion binding | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006826 | Iron ion transport | IEA | biological_process |
| GO:0006879 | Cellular iron ion homeostasis | TAS | biological_process |
| GO:0006892 | Post-Golgi vesicle-mediated transport | TAS | biological_process |
| GO:0008043 | Intracellular ferritin complex | IDA | cellular_component |
| GO:0008199 | Ferric iron binding | IEA | molecular_function |
| GO:0008219 | Cell death | IEA | biological_process |
| GO:0042802 | Identical protein binding | IPI | molecular_function |
| GO:0055072 | Iron ion homeostasis | TAS | biological_process |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0684309601 | 0.9782875803 | 0.5617352666 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2664428110 |
| GSE13712_SHEAR | Up | 0.1476739988 |
| GSE13712_STATIC | Down | -0.0284816130 |
| GSE19018 | Down | -0.3510111136 |
| GSE19899_A1 | Down | -0.0169340801 |
| GSE19899_A2 | Down | -0.0413523882 |
| PubMed_21979375_A1 | Up | 0.5141898597 |
| PubMed_21979375_A2 | Up | 0.1232303164 |
| GSE35957 | Up | 0.2277636821 |
| GSE36640 | Up | 0.8044196841 |
| GSE54402 | Up | 0.3809459896 |
| GSE9593 | Up | 0.2655085864 |
| GSE43922 | Up | 0.0140641400 |
| GSE24585 | Up | 0.4255973545 |
| GSE37065 | Up | 0.1279946158 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.1385755730 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-133a-3p | MIMAT0000427 | MIRT021706 | Microarray | Functional MTI (Weak) | 21396852 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031525 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
