HCSGD entry for ALPP


1. General information

Official gene symbolALPP
Entrez ID250
Gene full namealkaline phosphatase, placental
Other gene symbolsALP PALP PLAP PLAP-1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000287Magnesium ion bindingISSmolecular_function
GO:0004035Alkaline phosphatase activityIDA NASmolecular_function
GO:0005886Plasma membraneIEAcellular_component
GO:0008270Zinc ion bindingISSmolecular_function
GO:0009986Cell surfaceIDAcellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0016311DephosphorylationIDA NASbiological_process
GO:0031225Anchored component of membraneIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.43800287220.54765853500.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0041104245
GSE13712_SHEARUp0.0254746456
GSE13712_STATICUp0.0365399230
GSE19018Up0.0657445673
GSE19899_A1Up0.1545247085
GSE19899_A2Down-0.1992149080
PubMed_21979375_A1Down-0.0586228239
PubMed_21979375_A2Down-0.3573231979
GSE35957Up0.0905376057
GSE36640Up0.1398554793
GSE54402Down-0.0318415721
GSE9593Up0.1052378300
GSE43922Up0.0583911907
GSE24585Up0.2177029524
GSE37065Down-0.0335618252
GSE28863_A1Down-0.2397745380
GSE28863_A2Up0.1117179241
GSE28863_A3Up0.6113558363
GSE28863_A4Down-0.3308891446
GSE48662Up0.0693430217

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

METHYL-PHOSPHONIC ACID MONO-(4-NITRO-PHENYL) ESTERDB08413 -

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.