HCSGD entry for BCL2L13


1. General information

Official gene symbolBCL2L13
Entrez ID23786
Gene full nameBCL2-like 13 (apoptosis facilitator)
Other gene symbolsBCL-RAMBO Bcl2-L-13 MIL1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005634NucleusIEAcellular_component
GO:0005739MitochondrionNAScellular_component
GO:0006915Apoptotic processNASbiological_process
GO:0006919Activation of cysteine-type endopeptidase activity involved in apoptotic processNASbiological_process
GO:0008656Cysteine-type endopeptidase activator activity involved in apoptotic processNASmolecular_function
GO:0016021Integral component of membraneIDAcellular_component
GO:0031966Mitochondrial membraneIEAcellular_component
GO:0042981Regulation of apoptotic processIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.12783836480.95734720190.72726817891.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0968301797
GSE13712_SHEARUp0.2409575598
GSE13712_STATICUp0.3813526530
GSE19018Up0.1933994936
GSE19899_A1Up0.1136480368
GSE19899_A2Up0.1634640382
PubMed_21979375_A1Down-0.1356237350
PubMed_21979375_A2Down-0.1475735311
GSE35957Up0.0927978051
GSE36640Up0.2621573431
GSE54402Up0.1746765218
GSE9593Up0.4968661727
GSE43922Down-0.0862699149
GSE24585Up0.4931848914
GSE37065Up0.0611171556
GSE28863_A1Up0.1042390276
GSE28863_A2Down-0.0783885290
GSE28863_A3Down-0.0809976345
GSE28863_A4Up0.0255295125
GSE48662Up0.2659250358

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-215-5pMIMAT0000272MIRT024899MicroarrayFunctional MTI (Weak)19074876
hsa-miR-34a-5pMIMAT0000255MIRT025555SequencingFunctional MTI (Weak)20371350
hsa-miR-10a-5pMIMAT0000253MIRT025589SequencingFunctional MTI (Weak)20371350
hsa-miR-192-5pMIMAT0000222MIRT026746MicroarrayFunctional MTI (Weak)19074876
hsa-miR-1301-3pMIMAT0005797MIRT036025CLASHFunctional MTI (Weak)23622248
hsa-miR-125b-5pMIMAT0000423MIRT046068CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.