HCSGD entry for IL17RA
1. General information
| Official gene symbol | IL17RA |
|---|---|
| Entrez ID | 23765 |
| Gene full name | interleukin 17 receptor A |
| Other gene symbols | CANDF5 CD217 CDw217 IL-17RA IL17R hIL-17R |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0005887 | Integral component of plasma membrane | NAS | cellular_component |
| GO:0007166 | Cell surface receptor signaling pathway | NAS | biological_process |
| GO:0019221 | Cytokine-mediated signaling pathway | NAS | biological_process |
| GO:0030368 | Interleukin-17 receptor activity | NAS | molecular_function |
| GO:0032747 | Positive regulation of interleukin-23 production | IDA | biological_process |
| GO:0072537 | Fibroblast activation | IDA | biological_process |
| GO:1900017 | Positive regulation of cytokine production involved in inflammatory response | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1322469397 | 0.8383154249 | 0.7376883076 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0333822201 |
| GSE13712_SHEAR | Up | 0.2170723558 |
| GSE13712_STATIC | Up | 0.4088758386 |
| GSE19018 | Down | -0.0436635643 |
| GSE19899_A1 | Down | -0.0697885325 |
| GSE19899_A2 | Up | 0.3269580489 |
| PubMed_21979375_A1 | Up | 0.4523158897 |
| PubMed_21979375_A2 | Up | 0.3325349169 |
| GSE35957 | Down | -0.2001164523 |
| GSE36640 | Down | -0.4132769933 |
| GSE54402 | Down | -0.0637791181 |
| GSE9593 | Up | 0.4289162669 |
| GSE43922 | Up | 0.1030860991 |
| GSE24585 | Up | 0.3788778263 |
| GSE37065 | Up | 0.1179584131 |
| GSE28863_A1 | Up | 0.1867444167 |
| GSE28863_A2 | Up | 0.1907087970 |
| GSE28863_A3 | Up | 0.3050772863 |
| GSE28863_A4 | Down | -0.3347530135 |
| GSE48662 | Down | -0.0268859679 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-375 | MIMAT0000728 | MIRT019991 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049271 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
