HCSGD entry for PPIL2
1. General information
| Official gene symbol | PPIL2 |
|---|---|
| Entrez ID | 23759 |
| Gene full name | peptidylprolyl isomerase (cyclophilin)-like 2 |
| Other gene symbols | CYC4 CYP60 Cyp-60 UBOX7 hCyP-60 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000151 | Ubiquitin ligase complex | IEA | cellular_component |
| GO:0000209 | Protein polyubiquitination | IDA | biological_process |
| GO:0003755 | Peptidyl-prolyl cis-trans isomerase activity | IEA | molecular_function |
| GO:0004842 | Ubiquitin-protein ligase activity | IDA IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA TAS | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005796 | Golgi lumen | TAS | cellular_component |
| GO:0006457 | Protein folding | IEA | biological_process |
| GO:0007596 | Blood coagulation | TAS | biological_process |
| GO:0034450 | Ubiquitin-ubiquitin ligase activity | IDA | molecular_function |
| GO:0050900 | Leukocyte migration | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9799782189 | 0.2454375898 | 0.9999902473 | 0.9535160714 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0620314725 |
| GSE13712_SHEAR | Down | -0.0142783427 |
| GSE13712_STATIC | Up | 0.0561368924 |
| GSE19018 | Up | 0.1052349011 |
| GSE19899_A1 | Down | -0.0881270850 |
| GSE19899_A2 | Down | -0.0667624873 |
| PubMed_21979375_A1 | Down | -0.0775424094 |
| PubMed_21979375_A2 | Down | -0.1077546601 |
| GSE35957 | Up | 0.0364988898 |
| GSE36640 | Down | -0.3857520225 |
| GSE54402 | Down | -0.0213856231 |
| GSE9593 | Down | -0.1425421753 |
| GSE43922 | Down | -0.1994468411 |
| GSE24585 | Down | -0.0503721535 |
| GSE37065 | Down | -0.0498947277 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.2481285524 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-15b-5p | MIMAT0000417 | MIRT046489 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-31-5p | MIMAT0000089 | MIRT049857 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
