HCSGD entry for ARFIP2
1. General information
| Official gene symbol | ARFIP2 |
|---|---|
| Entrez ID | 23647 |
| Gene full name | ADP-ribosylation factor interacting protein 2 |
| Other gene symbols | POR1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001726 | Ruffle | IMP | cellular_component |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005525 | GTP binding | TAS | molecular_function |
| GO:0005737 | Cytoplasm | TAS | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005938 | Cell cortex | IDA | cellular_component |
| GO:0006928 | Cellular component movement | TAS | biological_process |
| GO:0007264 | Small GTPase mediated signal transduction | TAS | biological_process |
| GO:0019904 | Protein domain specific binding | IEA | molecular_function |
| GO:0030032 | Lamellipodium assembly | TAS | biological_process |
| GO:0030036 | Actin cytoskeleton organization | IMP | biological_process |
| GO:0030742 | GTP-dependent protein binding | IPI TAS | molecular_function |
| GO:0031529 | Ruffle organization | TAS | biological_process |
| GO:0048365 | Rac GTPase binding | TAS | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0067726188 | 0.9105027355 | 0.2160752727 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.6957465950 |
| GSE13712_SHEAR | Down | -0.0335808653 |
| GSE13712_STATIC | Up | 0.0134574703 |
| GSE19018 | Down | -0.3556688015 |
| GSE19899_A1 | Up | 0.6593994738 |
| GSE19899_A2 | Up | 1.7952400685 |
| PubMed_21979375_A1 | Up | 1.0683464815 |
| PubMed_21979375_A2 | Up | 1.4946592606 |
| GSE35957 | Down | -0.2340997186 |
| GSE36640 | Up | 0.3115928759 |
| GSE54402 | Up | 0.6520689176 |
| GSE9593 | Down | -0.1195829024 |
| GSE43922 | Up | 0.4518704983 |
| GSE24585 | Down | -0.0286415237 |
| GSE37065 | Down | -0.2113861110 |
| GSE28863_A1 | Up | 0.2656653950 |
| GSE28863_A2 | Up | 0.4742689477 |
| GSE28863_A3 | Down | -0.4433573933 |
| GSE28863_A4 | Up | 0.1755777511 |
| GSE48662 | Up | 0.1357838751 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT001570 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029664 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032409 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
