HCSGD entry for EDC4
1. General information
| Official gene symbol | EDC4 |
|---|---|
| Entrez ID | 23644 |
| Gene full name | enhancer of mRNA decapping 4 |
| Other gene symbols | GE1 Ge-1 HEDL5 HEDLS RCD-8 RCD8 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000288 | Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | TAS | biological_process |
| GO:0000932 | Cytoplasmic mRNA processing body | IDA | cellular_component |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | TAS | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0008150 | Biological_process | ND | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016070 | RNA metabolic process | TAS | biological_process |
| GO:0016071 | MRNA metabolic process | TAS | biological_process |
| GO:0043231 | Intracellular membrane-bounded organelle | IDA | cellular_component |
| GO:0043928 | Exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7502066943 | 0.1959510771 | 0.9999902473 | 0.8576036415 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2235901471 |
| GSE13712_SHEAR | Down | -0.1425925061 |
| GSE13712_STATIC | Down | -0.0243404531 |
| GSE19018 | Down | -0.3493302884 |
| GSE19899_A1 | Down | -0.4297263104 |
| GSE19899_A2 | Down | -0.3252578512 |
| PubMed_21979375_A1 | Up | 0.2175242588 |
| PubMed_21979375_A2 | Up | 0.0907944835 |
| GSE35957 | Down | -0.3746646038 |
| GSE36640 | Down | -0.2229547001 |
| GSE54402 | Up | 0.2863587191 |
| GSE9593 | Down | -0.2390743996 |
| GSE43922 | Up | 0.0057856235 |
| GSE24585 | Down | -0.1466362357 |
| GSE37065 | Down | -0.1959036093 |
| GSE28863_A1 | Up | 0.3600171903 |
| GSE28863_A2 | Up | 0.4258951618 |
| GSE28863_A3 | Down | -0.5777772330 |
| GSE28863_A4 | Up | 0.0511920279 |
| GSE48662 | Up | 0.0468368587 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT031748 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-1226-3p | MIMAT0005577 | MIRT036488 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-15b-5p | MIMAT0000417 | MIRT046437 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049266 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
