HCSGD entry for LY96

1. General information

Official gene symbolLY96
Entrez ID23643
Gene full namelymphocyte antigen 96
Other gene symbolsESOP-1 MD-2 MD2 ly-96
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001875Lipopolysaccharide receptor activityIDAmolecular_function
GO:0002224Toll-like receptor signaling pathwayTASbiological_process
GO:0002755MyD88-dependent toll-like receptor signaling pathwayTASbiological_process
GO:0002756MyD88-independent toll-like receptor signaling pathwayTASbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005615Extracellular spaceIEAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0006954Inflammatory responseIEAbiological_process
GO:0006968Cellular defense responseTASbiological_process
GO:0007166Cell surface receptor signaling pathwayTASbiological_process
GO:0007249I-kappaB kinase/NF-kappaB signalingTASbiological_process
GO:0010008Endosome membraneTAScellular_component
GO:0015026Coreceptor activityTASmolecular_function
GO:0031663Lipopolysaccharide-mediated signaling pathwayIDAbiological_process
GO:0031666Positive regulation of lipopolysaccharide-mediated signaling pathwayIEAbiological_process
GO:0032496Response to lipopolysaccharideIDAbiological_process
GO:0032497Detection of lipopolysaccharideIDAbiological_process
GO:0034134Toll-like receptor 2 signaling pathwayTASbiological_process
GO:0034138Toll-like receptor 3 signaling pathwayTASbiological_process
GO:0034142Toll-like receptor 4 signaling pathwayTASbiological_process
GO:0035666TRIF-dependent toll-like receptor signaling pathwayTASbiological_process
GO:0038123Toll-like receptor TLR1:TLR2 signaling pathwayTASbiological_process
GO:0038124Toll-like receptor TLR6:TLR2 signaling pathwayTASbiological_process
GO:0045087Innate immune responseTASbiological_process
GO:0046696Lipopolysaccharide receptor complexIDAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00017315830.99908430530.03890847461.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up1.1818506605
GSE13712_SHEARUp0.3641245076
GSE13712_STATICUp0.3206942346
GSE19018Up0.5883602603
GSE19899_A1Up1.0644928519
GSE19899_A2Up0.8222194018
PubMed_21979375_A1Up2.8111936560
PubMed_21979375_A2Up1.3816727651
GSE35957Up0.1330722027
GSE36640Up1.2045893530
GSE54402Up0.2244849325
GSE9593Up1.5365069265
GSE43922Up0.9198492470
GSE24585Up0.0438499051
GSE37065Up0.3583905860
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.5685298218

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

3-Hydroxy-Myristic AcidDB02767 EXPT01506
MYRISTIC ACIDDB08231 -

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.