HCSGD entry for HSPBP1
1. General information
| Official gene symbol | HSPBP1 |
|---|---|
| Entrez ID | 23640 |
| Gene full name | HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 |
| Other gene symbols | FES1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004857 | Enzyme inhibitor activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0006457 | Protein folding | TAS | biological_process |
| GO:0031398 | Positive regulation of protein ubiquitination | IDA | biological_process |
| GO:0032436 | Positive regulation of proteasomal ubiquitin-dependent protein catabolic process | IDA | biological_process |
| GO:0043086 | Negative regulation of catalytic activity | TAS | biological_process |
| GO:0050790 | Regulation of catalytic activity | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7082650925 | 0.2229189051 | 0.9999902473 | 0.9086957565 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1116715231 |
| GSE13712_SHEAR | Down | -0.2575046368 |
| GSE13712_STATIC | Up | 0.0115443175 |
| GSE19018 | Up | 0.1314749349 |
| GSE19899_A1 | Down | -0.1698449489 |
| GSE19899_A2 | Up | 0.4342273696 |
| PubMed_21979375_A1 | Up | 1.1219648281 |
| PubMed_21979375_A2 | Up | 0.2513882499 |
| GSE35957 | Down | -0.6064981412 |
| GSE36640 | Down | -0.3430726108 |
| GSE54402 | Up | 0.0480781137 |
| GSE9593 | Down | -0.4563007258 |
| GSE43922 | Up | 0.1041514035 |
| GSE24585 | Down | -0.3694113182 |
| GSE37065 | Down | -0.2824310368 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.3007626368 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-7-5p | MIMAT0000252 | MIRT025683 | Microarray | Functional MTI (Weak) | 19073608 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031614 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-484 | MIMAT0002174 | MIRT042390 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-125b-5p | MIMAT0000423 | MIRT046019 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049498 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
