HCSGD entry for RABGAP1
1. General information
| Official gene symbol | RABGAP1 |
|---|---|
| Entrez ID | 23637 |
| Gene full name | RAB GTPase activating protein 1 |
| Other gene symbols | GAPCENA RP11-123N4.2 TBC1D11 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0005096 | GTPase activator activity | TAS | molecular_function |
| GO:0005097 | Rab GTPase activator activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005813 | Centrosome | TAS | cellular_component |
| GO:0005829 | Cytosol | IEA | cellular_component |
| GO:0005875 | Microtubule associated complex | TAS | cellular_component |
| GO:0007049 | Cell cycle | IEA | biological_process |
| GO:0015631 | Tubulin binding | TAS | molecular_function |
| GO:0043085 | Positive regulation of catalytic activity | TAS | biological_process |
| GO:0043547 | Positive regulation of GTPase activity | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3507508377 | 0.3111816686 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0641228018 |
| GSE13712_SHEAR | Down | -0.2997374290 |
| GSE13712_STATIC | Down | -0.2491014247 |
| GSE19018 | Down | -0.0434142082 |
| GSE19899_A1 | Down | -0.4439845354 |
| GSE19899_A2 | Down | -0.1757341924 |
| PubMed_21979375_A1 | Down | -0.4320457800 |
| PubMed_21979375_A2 | Up | 0.1565489004 |
| GSE35957 | Down | -0.1446140410 |
| GSE36640 | Down | -0.0372161621 |
| GSE54402 | Up | 0.1130678262 |
| GSE9593 | Down | -0.1216244668 |
| GSE43922 | Down | -0.2766310554 |
| GSE24585 | Up | 0.5947030171 |
| GSE37065 | Up | 0.0680729923 |
| GSE28863_A1 | Up | 0.7453403726 |
| GSE28863_A2 | Up | 0.3134862775 |
| GSE28863_A3 | Down | -0.2748742286 |
| GSE28863_A4 | Up | 0.1224062628 |
| GSE48662 | Up | 0.2546461044 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-192-5p | MIMAT0000222 | MIRT004150 | Microarray | Functional MTI (Weak) | 16822819 |
| hsa-miR-9-5p | MIMAT0000441 | MIRT021450 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030972 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-93-3p | MIMAT0004509 | MIRT038856 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-504-5p | MIMAT0002875 | MIRT041085 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT048971 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
