HCSGD entry for FAM89B
1. General information
| Official gene symbol | FAM89B |
|---|---|
| Entrez ID | 23625 |
| Gene full name | family with sequence similarity 89, member B |
| Other gene symbols | MTVR1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001222 | Transcription corepressor binding | ISS | molecular_function |
| GO:0005737 | Cytoplasm | ISS | cellular_component |
| GO:0009986 | Cell surface | IEA | cellular_component |
| GO:0030512 | Negative regulation of transforming growth factor beta receptor signaling pathway | ISS | biological_process |
| GO:0060392 | Negative regulation of SMAD protein import into nucleus | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2756600965 | 0.4065695110 | 0.9714351854 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3742440967 |
| GSE13712_SHEAR | Down | -0.4265483547 |
| GSE13712_STATIC | Down | -0.3047531261 |
| GSE19018 | Up | 0.0657509539 |
| GSE19899_A1 | Down | -0.2895041806 |
| GSE19899_A2 | Up | 0.3757640361 |
| PubMed_21979375_A1 | Up | 1.1814217189 |
| PubMed_21979375_A2 | Up | 0.1859427562 |
| GSE35957 | Down | -0.3003093202 |
| GSE36640 | Up | 0.0494632004 |
| GSE54402 | Up | 0.3004244187 |
| GSE9593 | Up | 0.0121605141 |
| GSE43922 | Down | -0.0087155732 |
| GSE24585 | Down | -0.6133583239 |
| GSE37065 | Down | -0.1090960362 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.3016221541 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-7-5p | MIMAT0000252 | MIRT025771 | Microarray | Functional MTI (Weak) | 19073608 |
| hsa-miR-93-3p | MIMAT0004509 | MIRT038867 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
