HCSGD entry for CLEC5A

1. General information

Official gene symbolCLEC5A
Entrez ID23601
Gene full nameC-type lectin domain family 5, member A
Other gene symbolsCLECSF5 MDL-1 MDL1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001618Virus receptor activityIDAmolecular_function
GO:0002076Osteoblast developmentISSbiological_process
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006968Cellular defense responseTASbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0009615Response to virusIDAbiological_process
GO:0009986Cell surfaceISScellular_component
GO:0016032Viral processIEAbiological_process
GO:0030246Carbohydrate bindingIEAmolecular_function
GO:0033033Negative regulation of myeloid cell apoptotic processIEAbiological_process
GO:0043066Negative regulation of apoptotic processISSbiological_process
GO:0045087Innate immune responseIDA TASbiological_process
GO:0050715Positive regulation of cytokine secretionIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.38186084880.91102190270.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0735771109
GSE13712_SHEARDown-0.0060798536
GSE13712_STATICDown-0.0001732254
GSE19018Up0.0164695411
GSE19899_A1Up0.1424708077
GSE19899_A2Up0.3023941638
PubMed_21979375_A1Down-0.1125490148
PubMed_21979375_A2Up0.2432981367
GSE35957Down-0.2036943850
GSE36640Up0.0208214345
GSE54402Up0.1255627725
GSE9593Up0.0719673034
GSE43922Up0.0133152163
GSE24585Up0.2889281946
GSE37065Up0.0062575999
GSE28863_A1Up0.0184558152
GSE28863_A2Up0.1584178803
GSE28863_A3Up0.1546735821
GSE28863_A4Up0.0859145161
GSE48662Up0.0154801447

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-877-3pMIMAT0004950MIRT036848CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.