HCSGD entry for ORC3
1. General information
| Official gene symbol | ORC3 |
|---|---|
| Entrez ID | 23595 |
| Gene full name | origin recognition complex, subunit 3 |
| Other gene symbols | LAT LATHEO ORC3L |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000082 | G1/S transition of mitotic cell cycle | TAS | biological_process |
| GO:0000278 | Mitotic cell cycle | TAS | biological_process |
| GO:0000808 | Origin recognition complex | IDA | cellular_component |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003688 | DNA replication origin binding | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005664 | Nuclear origin of replication recognition complex | IDA IEA | cellular_component |
| GO:0006260 | DNA replication | IEA TAS | biological_process |
| GO:0061351 | Neural precursor cell proliferation | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4201835759 | 0.1935142016 | 0.9999902473 | 0.8528947254 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4216975404 |
| GSE13712_SHEAR | Down | -0.1410250674 |
| GSE13712_STATIC | Down | -0.0098748783 |
| GSE19018 | Up | 0.4948512858 |
| GSE19899_A1 | Down | -0.2478974299 |
| GSE19899_A2 | Down | -0.3213762773 |
| PubMed_21979375_A1 | Up | 0.1447679321 |
| PubMed_21979375_A2 | Down | -0.5952341240 |
| GSE35957 | Down | -0.1419561713 |
| GSE36640 | Down | -0.1110510611 |
| GSE54402 | Down | -0.1253716444 |
| GSE9593 | Down | -0.0912859018 |
| GSE43922 | Down | -0.0135865479 |
| GSE24585 | Up | 0.0563681828 |
| GSE37065 | Up | 0.0239744031 |
| GSE28863_A1 | Up | 0.1557518736 |
| GSE28863_A2 | Up | 0.8072440307 |
| GSE28863_A3 | Down | -0.5168587252 |
| GSE28863_A4 | Down | -0.2030178641 |
| GSE48662 | Down | -0.1389222279 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT023644 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
