HCSGD entry for ORC6
1. General information
| Official gene symbol | ORC6 |
|---|---|
| Entrez ID | 23594 |
| Gene full name | origin recognition complex, subunit 6 |
| Other gene symbols | ORC6L |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000082 | G1/S transition of mitotic cell cycle | TAS | biological_process |
| GO:0000278 | Mitotic cell cycle | TAS | biological_process |
| GO:0000808 | Origin recognition complex | IDA | cellular_component |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005664 | Nuclear origin of replication recognition complex | IEA | cellular_component |
| GO:0006260 | DNA replication | IEA TAS | biological_process |
| GO:0006261 | DNA-dependent DNA replication | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8060938604 | 0.0039064473 | 0.9999902473 | 0.1271456790 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3864888655 |
| GSE13712_SHEAR | Up | 1.2758269639 |
| GSE13712_STATIC | Up | 0.3583933078 |
| GSE19018 | Down | -0.1440752939 |
| GSE19899_A1 | Down | -0.8170316753 |
| GSE19899_A2 | Down | -1.0683257617 |
| PubMed_21979375_A1 | Down | -0.8256428578 |
| PubMed_21979375_A2 | Down | -1.9268485098 |
| GSE35957 | Down | -2.2902940157 |
| GSE36640 | Down | -1.4960952008 |
| GSE54402 | Down | -0.2678718759 |
| GSE9593 | Down | -0.9075754606 |
| GSE43922 | Up | 0.0486209986 |
| GSE24585 | Down | -0.1271569546 |
| GSE37065 | Down | -0.2378641222 |
| GSE28863_A1 | Down | -0.3139819079 |
| GSE28863_A2 | Up | 0.3970150157 |
| GSE28863_A3 | Up | 0.1376873971 |
| GSE28863_A4 | Up | 0.2611343759 |
| GSE48662 | Down | -0.4831586193 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016286 | Microarray | Functional MTI (Weak) | 20304954 |
| hsa-miR-484 | MIMAT0002174 | MIRT041879 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049645 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
