HCSGD entry for RBFOX2
1. General information
| Official gene symbol | RBFOX2 |
|---|---|
| Entrez ID | 23543 |
| Gene full name | RNA binding protein, fox-1 homolog (C. elegans) 2 |
| Other gene symbols | FOX2 Fox-2 HNRBP2 HRNBP2 RBM9 RTA dJ106I20.3 fxh |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0000381 | Regulation of alternative mRNA splicing, via spliceosome | ISS | biological_process |
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0003714 | Transcription corepressor activity | IDA | molecular_function |
| GO:0003723 | RNA binding | IDA IEA | molecular_function |
| GO:0003729 | MRNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006397 | MRNA processing | IEA | biological_process |
| GO:0008134 | Transcription factor binding | IDA | molecular_function |
| GO:0008380 | RNA splicing | IEA | biological_process |
| GO:0010724 | Regulation of definitive erythrocyte differentiation | IEA | biological_process |
| GO:0016070 | RNA metabolic process | TAS | biological_process |
| GO:0021942 | Radial glia guided migration of Purkinje cell | IEA | biological_process |
| GO:0030520 | Intracellular estrogen receptor signaling pathway | IDA | biological_process |
| GO:0042127 | Regulation of cell proliferation | TAS | biological_process |
| GO:0043484 | Regulation of RNA splicing | IEA | biological_process |
| GO:0045892 | Negative regulation of transcription, DNA-templated | IDA | biological_process |
| GO:0048813 | Dendrite morphogenesis | IEA | biological_process |
| GO:0050885 | Neuromuscular process controlling balance | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8975329129 | 0.0814495156 | 0.9999902473 | 0.5405689612 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0677021311 |
| GSE13712_SHEAR | Down | -0.2020609800 |
| GSE13712_STATIC | Down | -0.3197213824 |
| GSE19018 | Up | 0.0015332217 |
| GSE19899_A1 | Down | -0.6138126739 |
| GSE19899_A2 | Down | -0.5187797219 |
| PubMed_21979375_A1 | Down | -0.7360726946 |
| PubMed_21979375_A2 | Down | -0.9311032878 |
| GSE35957 | Down | -0.1072541030 |
| GSE36640 | Down | -0.3328622360 |
| GSE54402 | Down | -0.1793555078 |
| GSE9593 | Up | 0.1389477406 |
| GSE43922 | Down | -0.2489312456 |
| GSE24585 | Up | 0.3089153759 |
| GSE37065 | Down | -0.0448710451 |
| GSE28863_A1 | Up | 0.3921507668 |
| GSE28863_A2 | Up | 0.0408954983 |
| GSE28863_A3 | Down | -0.2020848331 |
| GSE28863_A4 | Up | 0.2752184887 |
| GSE48662 | Up | 0.2361779093 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-320d | MIMAT0006764 | MIRT007148 | Luciferase reporter assay | Functional MTI | 23418466 |
| hsa-miR-498 | MIMAT0002824 | MIRT007149 | Luciferase reporter assay | Functional MTI | 23418466 |
| hsa-miR-9-5p | MIMAT0000441 | MIRT021475 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-32-5p | MIMAT0000090 | MIRT028355 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028661 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032498 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032498 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT045228 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052619 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
