HCSGD entry for PRAME

1. General information

Official gene symbolPRAME
Entrez ID23532
Gene full namepreferentially expressed antigen in melanoma
Other gene symbolsCT130 MAPE OIP-4 OIP4
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005886Plasma membraneIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006915Apoptotic processIEAbiological_process
GO:0008284Positive regulation of cell proliferationIDA IEAbiological_process
GO:0030154Cell differentiationIEAbiological_process
GO:0040008Regulation of growthIEAbiological_process
GO:0042974Retinoic acid receptor bindingIDA IEAmolecular_function
GO:0043066Negative regulation of apoptotic processIDA IEAbiological_process
GO:0045596Negative regulation of cell differentiationIDA IEAbiological_process
GO:0045892Negative regulation of transcription, DNA-templatedIDA IEAbiological_process
GO:0048387Negative regulation of retinoic acid receptor signaling pathwayIDA IEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.96616184800.36112246500.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0948934643
GSE13712_SHEARDown-0.0861219434
GSE13712_STATICUp0.0104890162
GSE19018Down-0.1633113201
GSE19899_A1Up0.0461007093
GSE19899_A2Down-0.0007045326
PubMed_21979375_A1Down-0.0697421138
PubMed_21979375_A2Down-0.1246079920
GSE35957Up0.1367089653
GSE36640Down-0.0202421776
GSE54402Down-0.1250427143
GSE9593Up0.0429632036
GSE43922Up0.0113561598
GSE24585Down-0.2395873714
GSE37065Down-0.1344431327
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Down-0.0434753523

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.