HCSGD entry for ACAP2
1. General information
| Official gene symbol | ACAP2 |
|---|---|
| Entrez ID | 23527 |
| Gene full name | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 |
| Other gene symbols | CENTB2 CNT-B2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0008060 | ARF GTPase activator activity | IEA | molecular_function |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0010008 | Endosome membrane | ISS | cellular_component |
| GO:0032312 | Regulation of ARF GTPase activity | IEA | biological_process |
| GO:0036010 | Protein localization to endosome | ISS | biological_process |
| GO:1990090 | Cellular response to nerve growth factor stimulus | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0256457999 | 0.9307502071 | 0.3754387437 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2225662617 |
| GSE13712_SHEAR | Up | 0.1930918873 |
| GSE13712_STATIC | Up | 0.0368012706 |
| GSE19018 | Up | 0.3637944604 |
| GSE19899_A1 | Up | 0.3058152351 |
| GSE19899_A2 | Up | 0.6787693099 |
| PubMed_21979375_A1 | Up | 0.5301609888 |
| PubMed_21979375_A2 | Up | 1.0617915853 |
| GSE35957 | Up | 0.4021057553 |
| GSE36640 | Up | 0.7723712598 |
| GSE54402 | Up | 0.1952314591 |
| GSE9593 | Up | 0.2021536403 |
| GSE43922 | Up | 0.0387105767 |
| GSE24585 | Up | 0.2975190130 |
| GSE37065 | Up | 0.0460136837 |
| GSE28863_A1 | Up | 0.0978367938 |
| GSE28863_A2 | Up | 0.4410585817 |
| GSE28863_A3 | Down | -0.6508115124 |
| GSE28863_A4 | Down | -0.3198459186 |
| GSE48662 | Down | -0.7124270040 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-378a-3p | MIMAT0000732 | MIRT043930 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
