HCSGD entry for SRRM2
1. General information
| Official gene symbol | SRRM2 |
|---|---|
| Entrez ID | 23524 |
| Gene full name | serine/arginine repetitive matrix 2 |
| Other gene symbols | 300-KD CWF21 Cwc21 SRL300 SRm300 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000398 | MRNA splicing, via spliceosome | IC | biological_process |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0015030 | Cajal body | IDA | cellular_component |
| GO:0016607 | Nuclear speck | IDA | cellular_component |
| GO:0047485 | Protein N-terminus binding | IPI | molecular_function |
| GO:0070742 | C2H2 zinc finger domain binding | IDA | molecular_function |
| GO:0071013 | Catalytic step 2 spliceosome | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1657671289 | 0.6465647430 | 0.8057123432 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2011818503 |
| GSE13712_SHEAR | Down | -0.0409970467 |
| GSE13712_STATIC | Down | -0.2323386087 |
| GSE19018 | Down | -0.0557927070 |
| GSE19899_A1 | Up | 0.0797736275 |
| GSE19899_A2 | Up | 0.2212856562 |
| PubMed_21979375_A1 | Down | -0.3010068505 |
| PubMed_21979375_A2 | Up | 0.0405734854 |
| GSE35957 | Down | -0.1687525658 |
| GSE36640 | Up | 0.0298222163 |
| GSE54402 | Down | -0.0188247587 |
| GSE9593 | Down | -0.1578829021 |
| GSE43922 | Down | -0.0168867967 |
| GSE24585 | Down | -0.0029308140 |
| GSE37065 | Up | 0.0000623323 |
| GSE28863_A1 | Up | 1.2123746291 |
| GSE28863_A2 | Up | 0.8588647889 |
| GSE28863_A3 | Up | 0.4536146977 |
| GSE28863_A4 | Down | -0.0150678744 |
| GSE48662 | Up | 0.2405940051 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025333 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029360 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-877-5p | MIMAT0004949 | MIRT037298 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-744-5p | MIMAT0004945 | MIRT037385 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-455-3p | MIMAT0004784 | MIRT037831 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-505-5p | MIMAT0004776 | MIRT037946 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-769-3p | MIMAT0003887 | MIRT039116 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-769-5p | MIMAT0003886 | MIRT039202 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040335 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-18a-3p | MIMAT0002891 | MIRT040916 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-504-5p | MIMAT0002875 | MIRT041079 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-3p | MIMAT0000762 | MIRT042938 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043382 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044591 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT045088 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-125b-5p | MIMAT0000423 | MIRT045978 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046785 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-181b-5p | MIMAT0000257 | MIRT047263 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-31-5p | MIMAT0000089 | MIRT049895 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-25-3p | MIMAT0000081 | MIRT050213 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
