HCSGD entry for SKIV2L2
1. General information
| Official gene symbol | SKIV2L2 |
|---|---|
| Entrez ID | 23517 |
| Gene full name | superkiller viralicidic activity 2-like 2 (S. cerevisiae) |
| Other gene symbols | Dob1 KIAA0052 Mtr4 fSAP118 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000178 | Exosome (RNase complex) | IDA | cellular_component |
| GO:0000398 | MRNA splicing, via spliceosome | IC | biological_process |
| GO:0000460 | Maturation of 5.8S rRNA | IMP | biological_process |
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IEA | cellular_component |
| GO:0008026 | ATP-dependent helicase activity | IEA | molecular_function |
| GO:0016818 | Hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | IEA | molecular_function |
| GO:0071013 | Catalytic step 2 spliceosome | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8888256221 | 0.1994676798 | 0.9999902473 | 0.8638617966 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0160498316 |
| GSE13712_SHEAR | Down | -0.1540092586 |
| GSE13712_STATIC | Up | 0.1397793178 |
| GSE19018 | Down | -0.2809744055 |
| GSE19899_A1 | Up | 0.0542095701 |
| GSE19899_A2 | Down | -0.1043697893 |
| PubMed_21979375_A1 | Up | 0.4350611144 |
| PubMed_21979375_A2 | Down | -0.0513206746 |
| GSE35957 | Up | 0.0969493265 |
| GSE36640 | Down | -0.2227053864 |
| GSE54402 | Up | 0.0024373150 |
| GSE9593 | Down | -0.0756661355 |
| GSE43922 | Down | -0.0468879954 |
| GSE24585 | Down | -0.0880310549 |
| GSE37065 | Down | -0.0072086832 |
| GSE28863_A1 | Up | 0.1175288172 |
| GSE28863_A2 | Up | 0.3740626668 |
| GSE28863_A3 | Down | -0.6540570500 |
| GSE28863_A4 | Down | -0.2623980067 |
| GSE48662 | Down | -0.2932412811 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020972 | Proteomics | Functional MTI (Weak) | 20584899 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030044 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
