HCSGD entry for POFUT1
1. General information
| Official gene symbol | POFUT1 |
|---|---|
| Entrez ID | 23509 |
| Gene full name | protein O-fucosyltransferase 1 |
| Other gene symbols | FUT12 O-FUT O-Fuc-T O-FucT-1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001525 | Angiogenesis | IEA | biological_process |
| GO:0001756 | Somitogenesis | IEA | biological_process |
| GO:0005783 | Endoplasmic reticulum | IDA IEA | cellular_component |
| GO:0006004 | Fucose metabolic process | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | NAS | biological_process |
| GO:0006493 | Protein O-linked glycosylation | IDA | biological_process |
| GO:0007219 | Notch signaling pathway | IEA NAS TAS | biological_process |
| GO:0007399 | Nervous system development | IEA | biological_process |
| GO:0007507 | Heart development | IEA | biological_process |
| GO:0008417 | Fucosyltransferase activity | IDA | molecular_function |
| GO:0009790 | Embryo development | NAS | biological_process |
| GO:0016020 | Membrane | IDA | cellular_component |
| GO:0016266 | O-glycan processing | TAS | biological_process |
| GO:0016757 | Transferase activity, transferring glycosyl groups | IEA | molecular_function |
| GO:0036066 | Protein O-linked fucosylation | IDA | biological_process |
| GO:0046922 | Peptide-O-fucosyltransferase activity | IDA TAS | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7230243190 | 0.5589086395 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0460131297 |
| GSE13712_SHEAR | Down | -0.0241839431 |
| GSE13712_STATIC | Up | 0.1006471855 |
| GSE19018 | Up | 0.0994610340 |
| GSE19899_A1 | Down | -0.0186120248 |
| GSE19899_A2 | Down | -0.1136972002 |
| PubMed_21979375_A1 | Down | -0.8788062853 |
| PubMed_21979375_A2 | Down | -0.1307201535 |
| GSE35957 | Up | 0.0334178996 |
| GSE36640 | Up | 0.1594615542 |
| GSE54402 | Down | -0.2225956653 |
| GSE9593 | Up | 0.2007419678 |
| GSE43922 | Up | 0.0024003100 |
| GSE24585 | Down | -0.0037059851 |
| GSE37065 | Down | -0.0553858842 |
| GSE28863_A1 | Up | 0.1716754715 |
| GSE28863_A2 | Down | -0.0082450332 |
| GSE28863_A3 | Up | 0.2764561512 |
| GSE28863_A4 | Up | 0.0406791929 |
| GSE48662 | Up | 0.0269439759 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022339 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-122-5p | MIMAT0000421 | MIRT023228 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-148a-3p | MIMAT0000243 | MIRT025975 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031483 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-92b-3p | MIMAT0003218 | MIRT040628 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
