HCSGD entry for CBX6


1. General information

Official gene symbolCBX6
Entrez ID23466
Gene full namechromobox homolog 6
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIMPbiological_process
GO:0000792HeterochromatinIEAcellular_component
GO:0003727Single-stranded RNA bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDA IEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0016568Chromatin modificationIEAbiological_process
GO:0031519PcG protein complexIDAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.10366745940.41778185860.66955745831.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2852177238
GSE13712_SHEARDown-0.8127376719
GSE13712_STATICDown-0.4061441961
GSE19018Down-0.4889880733
GSE19899_A1Up0.0978329001
GSE19899_A2Up0.5463262534
PubMed_21979375_A1Down-0.0825629124
PubMed_21979375_A2Up0.5596539426
GSE35957Up0.1836063482
GSE36640Up0.6079087033
GSE54402Up0.1315904372
GSE9593Up0.1437815458
GSE43922Up0.0812040207
GSE24585Down-0.6318224076
GSE37065Down-0.1353609068
GSE28863_A1Up0.5383957629
GSE28863_A2Up0.3646429991
GSE28863_A3Down-0.0522539203
GSE28863_A4Down-0.1239311260
GSE48662Up0.4132641152

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT029448MicroarrayFunctional MTI (Weak)19088304
hsa-miR-874-3pMIMAT0004911MIRT037768CLASHFunctional MTI (Weak)23622248
hsa-miR-615-3pMIMAT0003283MIRT039667CLASHFunctional MTI (Weak)23622248
hsa-miR-484MIMAT0002174MIRT041709CLASHFunctional MTI (Weak)23622248
hsa-miR-328-3pMIMAT0000752MIRT043813CLASHFunctional MTI (Weak)23622248
hsa-miR-182-5pMIMAT0000259MIRT047178CLASHFunctional MTI (Weak)23622248
hsa-miR-92a-3pMIMAT0000092MIRT049019CLASHFunctional MTI (Weak)23622248
hsa-let-7c-5pMIMAT0000064MIRT051814CLASHFunctional MTI (Weak)23622248
hsa-let-7b-5pMIMAT0000063MIRT052310CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.