HCSGD entry for FOLH1

1. General information

Official gene symbolFOLH1
Entrez ID2346
Gene full namefolate hydrolase (prostate-specific membrane antigen) 1
Other gene symbolsFGCP FOLH GCP2 GCPII NAALAD1 NAALAdase PSM PSMA mGCP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004180Carboxypeptidase activityIEAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005887Integral component of plasma membraneIEAcellular_component
GO:0006508ProteolysisIEA NASbiological_process
GO:0006760Folic acid-containing compound metabolic processIEAbiological_process
GO:0008233Peptidase activityNASmolecular_function
GO:0008237Metallopeptidase activityIEAmolecular_function
GO:0016020MembraneNAScellular_component
GO:0016805Dipeptidase activityIEAmolecular_function
GO:0046872Metal ion bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.90095124810.54704056840.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1169443046
GSE13712_SHEARUp0.0671816888
GSE13712_STATICDown-0.2465310787
GSE19018Up0.0180664195
GSE19899_A1Up0.0622406524
GSE19899_A2Up0.0408305989
PubMed_21979375_A1Up0.2305794370
PubMed_21979375_A2Down-0.1127030251
GSE35957Down-0.0101914776
GSE36640Up0.0871548727
GSE54402Up0.0088873057
GSE9593Down-0.1237118662
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1Down-0.0951023529
GSE28863_A2Down-0.1497027530
GSE28863_A3Up0.0696426623
GSE28863_A4Down-0.0175864517
GSE48662Up0.0095517805

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

CapromabDB00089 BTD00080 | BIOD00080
L-Glutamic AcidDB00142 NUTR00027
(2S)-2-{[HYDROXY(4-IODOBENZYL)PHOSPHORYL]METHYL}PENTANEDIOIC ACIDDB06928 -
N-({(1R)-1-carboxy-2-[(4-fluorobenzyl)sulfanyl]ethyl}carbamoyl)-L-glutamic acidDB07754 -

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT029538MicroarrayFunctional MTI (Weak)19088304
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.