HCSGD entry for ITGB3BP

1. General information

Official gene symbolITGB3BP
Entrez ID23421
Gene full nameintegrin beta 3 binding protein (beta3-endonexin)
Other gene symbolsCENP-R CENPR HSU37139 NRIF3 TAP20
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000278Mitotic cell cycleTASbiological_process
GO:0000777Condensed chromosome kinetochoreIEAcellular_component
GO:0004871Signal transducer activityTASmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmTAScellular_component
GO:0005829CytosolTAScellular_component
GO:0006334Nucleosome assemblyTASbiological_process
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006355Regulation of transcription, DNA-templatedIEAbiological_process
GO:0007067MitosisIEAbiological_process
GO:0007155Cell adhesionTASbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0008022Protein C-terminus bindingTASmolecular_function
GO:0016020MembraneTAScellular_component
GO:0034080CENP-A containing nucleosome assembly at centromereTASbiological_process
GO:0043065Positive regulation of apoptotic processTASbiological_process
GO:0048011Neurotrophin TRK receptor signaling pathwayTASbiological_process
GO:0097190Apoptotic signaling pathwayTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.52454333800.00013094870.99999024730.0202052326

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-1.4148480062
GSE13712_SHEARDown-0.0819399878
GSE13712_STATICDown-0.1189584436
GSE19018Up0.7962238027
GSE19899_A1Down-1.1637938211
GSE19899_A2Down-4.4489189622
PubMed_21979375_A1Down-3.0185094134
PubMed_21979375_A2Down-4.8066807784
GSE35957Down-1.6821758719
GSE36640Down-4.3894021104
GSE54402Down-0.7969224240
GSE9593Down-0.7269437175
GSE43922Down-1.5661141623
GSE24585Up0.1107163447
GSE37065Up0.2448338496
GSE28863_A1Up0.1215292343
GSE28863_A2Up1.2572448794
GSE28863_A3Down-0.4867403497
GSE28863_A4Down-0.2778124958
GSE48662Down-0.1835650495

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-9-5pMIMAT0000441MIRT045781CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.