HCSGD entry for CRB1
1. General information
| Official gene symbol | CRB1 |
|---|---|
| Entrez ID | 23418 |
| Gene full name | crumbs homolog 1 (Drosophila) |
| Other gene symbols | LCA8 RP12 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0005902 | Microvillus | IEA | cellular_component |
| GO:0007009 | Plasma membrane organization | IEA | biological_process |
| GO:0007163 | Establishment or maintenance of cell polarity | TAS | biological_process |
| GO:0007267 | Cell-cell signaling | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016324 | Apical plasma membrane | IEA | cellular_component |
| GO:0042462 | Eye photoreceptor cell development | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7106850006 | 0.9007970784 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0911846754 |
| GSE13712_SHEAR | Up | 0.1435957968 |
| GSE13712_STATIC | Up | 0.0950757607 |
| GSE19018 | Up | 0.1187985559 |
| GSE19899_A1 | Up | 0.0470683798 |
| GSE19899_A2 | Up | 0.0118643612 |
| PubMed_21979375_A1 | Down | -0.0879697003 |
| PubMed_21979375_A2 | Down | -0.1098138764 |
| GSE35957 | Up | 0.1573863746 |
| GSE36640 | Up | 0.0530203064 |
| GSE54402 | Up | 0.0792844391 |
| GSE9593 | Up | 0.0701944931 |
| GSE43922 | Up | 0.0141269957 |
| GSE24585 | Up | 0.0303228786 |
| GSE37065 | Up | 0.0290302446 |
| GSE28863_A1 | Down | -0.0012253683 |
| GSE28863_A2 | Up | 0.0853176513 |
| GSE28863_A3 | Up | 0.0152474957 |
| GSE28863_A4 | Up | 0.1086989995 |
| GSE48662 | Up | 0.0261237033 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022890 | Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
