HCSGD entry for PIP5K1C
1. General information
| Official gene symbol | PIP5K1C |
|---|---|
| Entrez ID | 23396 |
| Gene full name | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| Other gene symbols | LCCS3 PIP5K-GAMMA PIP5Kgamma PIPKIg_v4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001891 | Phagocytic cup | IEA | cellular_component |
| GO:0001931 | Uropod | TAS | cellular_component |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005925 | Focal adhesion | TAS | cellular_component |
| GO:0006644 | Phospholipid metabolic process | TAS | biological_process |
| GO:0006661 | Phosphatidylinositol biosynthetic process | TAS | biological_process |
| GO:0006909 | Phagocytosis | TAS | biological_process |
| GO:0007016 | Cytoskeletal anchoring at plasma membrane | IEA | biological_process |
| GO:0007411 | Axon guidance | TAS | biological_process |
| GO:0012505 | Endomembrane system | IEA | cellular_component |
| GO:0016079 | Synaptic vesicle exocytosis | TAS | biological_process |
| GO:0016308 | 1-phosphatidylinositol-4-phosphate 5-kinase activity | IEA | molecular_function |
| GO:0016337 | Cell-cell adhesion | TAS | biological_process |
| GO:0030036 | Actin cytoskeleton organization | TAS | biological_process |
| GO:0030593 | Neutrophil chemotaxis | TAS | biological_process |
| GO:0032587 | Ruffle membrane | IEA | cellular_component |
| GO:0034333 | Adherens junction assembly | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0048488 | Synaptic vesicle endocytosis | TAS | biological_process |
| GO:0070527 | Platelet aggregation | IEA | biological_process |
| GO:0072583 | Clathrin-mediated endocytosis | TAS | biological_process |
| GO:1990147 | Talin binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0077894609 | 0.9536289009 | 0.2285690078 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0618806555 |
| GSE13712_SHEAR | Up | 0.2428067348 |
| GSE13712_STATIC | Up | 0.1341130670 |
| GSE19018 | Down | -0.2204026783 |
| GSE19899_A1 | Up | 0.3485028927 |
| GSE19899_A2 | Up | 0.6748810030 |
| PubMed_21979375_A1 | Up | 0.8187304258 |
| PubMed_21979375_A2 | Up | 3.6696760773 |
| GSE35957 | Down | -0.0118461497 |
| GSE36640 | Up | 1.0385195756 |
| GSE54402 | Up | 0.2763299705 |
| GSE9593 | Up | 0.6124108409 |
| GSE43922 | Up | 0.1204246629 |
| GSE24585 | Down | -0.0706123194 |
| GSE37065 | Down | -0.0757123043 |
| GSE28863_A1 | Up | 0.3277239112 |
| GSE28863_A2 | Up | 0.4623638653 |
| GSE28863_A3 | Up | 0.0038231125 |
| GSE28863_A4 | Down | -0.0679657148 |
| GSE48662 | Up | 0.4800702007 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-101-3p | MIMAT0000099 | MIRT027379 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-32-5p | MIMAT0000090 | MIRT028353 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030015 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041364 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
