HCSGD entry for ADNP
1. General information
| Official gene symbol | ADNP |
|---|---|
| Entrez ID | 23394 |
| Gene full name | activity-dependent neuroprotector homeobox |
| Other gene symbols | ADNP1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003682 | Chromatin binding | IEA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005615 | Extracellular space | IEA | cellular_component |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0043524 | Negative regulation of neuron apoptotic process | IEA | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8668793055 | 0.0860575852 | 0.9999902473 | 0.5574998031 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3746692814 |
| GSE13712_SHEAR | Down | -0.0161828412 |
| GSE13712_STATIC | Up | 0.0031885858 |
| GSE19018 | Up | 0.0953810014 |
| GSE19899_A1 | Down | -0.2316094525 |
| GSE19899_A2 | Down | -0.4321661227 |
| PubMed_21979375_A1 | Down | -0.2615914215 |
| PubMed_21979375_A2 | Down | -0.3149086994 |
| GSE35957 | Down | -0.2769968061 |
| GSE36640 | Down | -0.5980039647 |
| GSE54402 | Up | 0.0328983363 |
| GSE9593 | Down | -0.2898381757 |
| GSE43922 | Down | -0.1379549815 |
| GSE24585 | Down | -0.0553407259 |
| GSE37065 | Up | 0.0167551002 |
| GSE28863_A1 | Up | 0.7499015646 |
| GSE28863_A2 | Up | 0.4617270204 |
| GSE28863_A3 | Up | 0.1396407465 |
| GSE28863_A4 | Up | 0.0794401262 |
| GSE48662 | Down | -0.6320491197 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025421 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029262 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030862 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-328-3p | MIMAT0000752 | MIRT043763 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052249 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
