HCSGD entry for TENC1
1. General information
| Official gene symbol | TENC1 |
|---|---|
| Entrez ID | 23371 |
| Gene full name | tensin like C1 domain containing phosphatase (tensin 2) |
| Other gene symbols | C1-TEN C1TEN TNS2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001822 | Kidney development | IEA | biological_process |
| GO:0004721 | Phosphoprotein phosphatase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0005925 | Focal adhesion | IDA | cellular_component |
| GO:0008285 | Negative regulation of cell proliferation | IMP | biological_process |
| GO:0014850 | Response to muscle activity | IEA | biological_process |
| GO:0019725 | Cellular homeostasis | IEA | biological_process |
| GO:0032963 | Collagen metabolic process | IEA | biological_process |
| GO:0035264 | Multicellular organism growth | IEA | biological_process |
| GO:0035556 | Intracellular signal transduction | IEA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0048871 | Multicellular organismal homeostasis | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8789021922 | 0.0106631435 | 0.9999902473 | 0.2045660350 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2112150720 |
| GSE13712_SHEAR | Down | -0.5609204782 |
| GSE13712_STATIC | Down | -0.9281151640 |
| GSE19018 | Up | 0.1880910915 |
| GSE19899_A1 | Down | -0.2308860369 |
| GSE19899_A2 | Down | -0.8865841393 |
| PubMed_21979375_A1 | Down | -1.4112993136 |
| PubMed_21979375_A2 | Down | -0.1452066176 |
| GSE35957 | Down | -0.4033163505 |
| GSE36640 | Down | -0.2702791647 |
| GSE54402 | Down | -1.2639849235 |
| GSE9593 | Down | -0.2693781372 |
| GSE43922 | Down | -0.4331547390 |
| GSE24585 | Up | 0.5321516269 |
| GSE37065 | Down | -0.3505204234 |
| GSE28863_A1 | Up | 0.7932844350 |
| GSE28863_A2 | Up | 0.3409333968 |
| GSE28863_A3 | Down | -0.2125370335 |
| GSE28863_A4 | Down | -0.1100170750 |
| GSE48662 | Down | -0.0635996861 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018978 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030195 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
