HCSGD entry for SMCHD1
1. General information
| Official gene symbol | SMCHD1 |
|---|---|
| Entrez ID | 23347 |
| Gene full name | structural maintenance of chromosomes flexible hinge domain containing 1 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001740 | Barr body | IEA | cellular_component |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005694 | Chromosome | IEA | cellular_component |
| GO:0051276 | Chromosome organization | IEA | biological_process |
| GO:0060821 | Inactivation of X chromosome by DNA methylation | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6077606930 | 0.0287548611 | 0.9999902473 | 0.3221988936 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0032988346 |
| GSE13712_SHEAR | Up | 0.1941111324 |
| GSE13712_STATIC | Up | 0.1344420611 |
| GSE19018 | Down | -0.3028239334 |
| GSE19899_A1 | Down | -0.4978755177 |
| GSE19899_A2 | Down | -1.0258627782 |
| PubMed_21979375_A1 | Down | -0.8929434721 |
| PubMed_21979375_A2 | Down | -0.5835088791 |
| GSE35957 | Down | -0.4004365185 |
| GSE36640 | Down | -1.0220637695 |
| GSE54402 | Down | -0.4065450282 |
| GSE9593 | Down | -0.1024098750 |
| GSE43922 | Down | -0.4707637868 |
| GSE24585 | Down | -0.0645854188 |
| GSE37065 | Up | 0.2277688254 |
| GSE28863_A1 | Up | 0.9853831887 |
| GSE28863_A2 | Up | 0.8015398140 |
| GSE28863_A3 | Down | -0.0605007353 |
| GSE28863_A4 | Up | 0.2482554386 |
| GSE48662 | Down | -0.2873040824 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-210-3p | MIMAT0000267 | MIRT003173 | immunoprecipitaion//Microarray//qRT-PCR | Functional MTI (Weak) | 19826008 |
| hsa-miR-132-3p | MIMAT0000426 | MIRT021727 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-128-3p | MIMAT0000424 | MIRT021952 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-181a-5p | MIMAT0000256 | MIRT025085 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-877-5p | MIMAT0004949 | MIRT037356 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-421 | MIMAT0003339 | MIRT039446 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045406 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-221-3p | MIMAT0000278 | MIRT046851 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10b-5p | MIMAT0000254 | MIRT047425 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047549 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-100-5p | MIMAT0000098 | MIRT048562 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT049938 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-18a-5p | MIMAT0000072 | MIRT050718 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
