HCSGD entry for AFF2
1. General information
| Official gene symbol | AFF2 |
|---|---|
| Entrez ID | 2334 |
| Gene full name | AF4/FMR2 family, member 2 |
| Other gene symbols | FMR2 FMR2P FRAXE MRX2 OX19 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002151 | G-quadruplex RNA binding | ISS | molecular_function |
| GO:0006397 | MRNA processing | IEA | biological_process |
| GO:0007420 | Brain development | TAS | biological_process |
| GO:0007611 | Learning or memory | IEA | biological_process |
| GO:0008380 | RNA splicing | IEA | biological_process |
| GO:0016607 | Nuclear speck | IDA | cellular_component |
| GO:0043484 | Regulation of RNA splicing | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3877460735 | 0.7011855591 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0668688913 |
| GSE13712_SHEAR | Down | -0.0780581225 |
| GSE13712_STATIC | Down | -0.1734294194 |
| GSE19018 | Up | 0.0993101161 |
| GSE19899_A1 | Up | 0.1082780410 |
| GSE19899_A2 | Up | 0.0183718441 |
| PubMed_21979375_A1 | Down | -0.0210335966 |
| PubMed_21979375_A2 | Up | 0.1713650702 |
| GSE35957 | Up | 0.2000985542 |
| GSE36640 | Up | 0.3694660867 |
| GSE54402 | Up | 0.1035805739 |
| GSE9593 | Up | 0.0036199492 |
| GSE43922 | Up | 0.0375785505 |
| GSE24585 | Down | -0.6651454798 |
| GSE37065 | Up | 0.1145945698 |
| GSE28863_A1 | Up | 0.3244145402 |
| GSE28863_A2 | Down | -0.3842750214 |
| GSE28863_A3 | Up | 0.3597750498 |
| GSE28863_A4 | Down | -0.0411885560 |
| GSE48662 | Up | 0.1180910271 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
