HCSGD entry for SYNM
1. General information
| Official gene symbol | SYNM |
|---|---|
| Entrez ID | 23336 |
| Gene full name | synemin, intermediate filament protein |
| Other gene symbols | DMN SYN |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005198 | Structural molecule activity | IEA | molecular_function |
| GO:0005200 | Structural constituent of cytoskeleton | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005882 | Intermediate filament | IDA IEA NAS | cellular_component |
| GO:0005912 | Adherens junction | IDA | cellular_component |
| GO:0008307 | Structural constituent of muscle | IDA | molecular_function |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0017166 | Vinculin binding | IDA | molecular_function |
| GO:0019215 | Intermediate filament binding | ISS | molecular_function |
| GO:0043034 | Costamere | IDA | cellular_component |
| GO:0045104 | Intermediate filament cytoskeleton organization | TAS | biological_process |
| GO:0060053 | Neurofilament cytoskeleton | TAS | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8702037423 | 0.0221893659 | 0.9999902473 | 0.2864271659 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3537468292 |
| GSE13712_SHEAR | Down | -0.5078384285 |
| GSE13712_STATIC | Down | -0.7104584783 |
| GSE19018 | Down | -0.5084914934 |
| GSE19899_A1 | Down | -0.8513840269 |
| GSE19899_A2 | Down | -0.6379993881 |
| PubMed_21979375_A1 | Down | -1.4940882530 |
| PubMed_21979375_A2 | Down | -0.1090286866 |
| GSE35957 | Up | 0.4299317576 |
| GSE36640 | Down | -0.1879086153 |
| GSE54402 | Down | -0.1273961556 |
| GSE9593 | Up | 0.0361127618 |
| GSE43922 | Down | -0.1150061134 |
| GSE24585 | Up | 0.1800854943 |
| GSE37065 | Down | -0.0430289885 |
| GSE28863_A1 | Up | 0.0503345992 |
| GSE28863_A2 | Up | 0.0448992484 |
| GSE28863_A3 | Up | 0.4337277059 |
| GSE28863_A4 | Up | 0.2259582721 |
| GSE48662 | Down | -0.1178796102 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-331-3p | MIMAT0000760 | MIRT043331 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
