HCSGD entry for MAN2B2
1. General information
| Official gene symbol | MAN2B2 |
|---|---|
| Entrez ID | 23324 |
| Gene full name | mannosidase, alpha, class 2B, member 2 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004559 | Alpha-mannosidase activity | IEA | molecular_function |
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0005764 | Lysosome | IEA | cellular_component |
| GO:0006013 | Mannose metabolic process | IEA | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0030246 | Carbohydrate binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0123297367 | 0.0654226093 | 0.2773769231 | 0.4832242985 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2268684231 |
| GSE13712_SHEAR | Up | 0.3353764964 |
| GSE13712_STATIC | Up | 0.6108189705 |
| GSE19018 | Up | 0.9651242743 |
| GSE19899_A1 | Down | -1.6856606903 |
| GSE19899_A2 | Down | -1.0136453559 |
| PubMed_21979375_A1 | Down | -2.0674829294 |
| PubMed_21979375_A2 | Down | -1.0558800931 |
| GSE35957 | Up | 0.3813362878 |
| GSE36640 | Up | 1.4650772846 |
| GSE54402 | Down | -0.9081937985 |
| GSE9593 | Up | 1.0473460529 |
| GSE43922 | Down | -0.5731733921 |
| GSE24585 | Up | 0.4835839483 |
| GSE37065 | Down | -0.0052815982 |
| GSE28863_A1 | Up | 0.8058584176 |
| GSE28863_A2 | Up | 0.9400157473 |
| GSE28863_A3 | Up | 0.1516639343 |
| GSE28863_A4 | Down | -0.2799431465 |
| GSE48662 | Up | 0.3864711589 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
