HCSGD entry for TRIM2
1. General information
| Official gene symbol | TRIM2 |
|---|---|
| Entrez ID | 23321 |
| Gene full name | tripartite motif containing 2 |
| Other gene symbols | RNF86 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004842 | Ubiquitin-protein ligase activity | IEA ISS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005622 | Intracellular | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0008270 | Zinc ion binding | IEA NAS | molecular_function |
| GO:0043523 | Regulation of neuron apoptotic process | IEA ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4721862315 | 0.5798094943 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3866743118 |
| GSE13712_SHEAR | Down | -0.2170091390 |
| GSE13712_STATIC | Up | 0.0197220149 |
| GSE19018 | Up | 0.1956415040 |
| GSE19899_A1 | Up | 0.0813835422 |
| GSE19899_A2 | Down | -0.0094021184 |
| PubMed_21979375_A1 | Down | -0.2891008787 |
| PubMed_21979375_A2 | Up | 0.2691226920 |
| GSE35957 | Up | 0.3355631480 |
| GSE36640 | Up | 0.1162929346 |
| GSE54402 | Up | 0.0117677109 |
| GSE9593 | Up | 0.0755208218 |
| GSE43922 | Down | -0.1773900161 |
| GSE24585 | Down | -0.0934268182 |
| GSE37065 | Up | 0.2469227421 |
| GSE28863_A1 | Down | -0.1166055606 |
| GSE28863_A2 | Down | -0.0037535380 |
| GSE28863_A3 | Down | -0.3801975664 |
| GSE28863_A4 | Up | 0.0023629965 |
| GSE48662 | Down | -0.2897994940 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT002748 | Microarray//Microarray;Other | Functional MTI (Weak) | 15685193 |
| hsa-miR-181c-5p | MIMAT0000258 | MIRT006877 | In situ hybridization//Luciferase reporter assay | Functional MTI | 21720722 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT017162 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-130b-3p | MIMAT0000691 | MIRT020230 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-181a-5p | MIMAT0000256 | MIRT025122 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT025626 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030775 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031116 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT045106 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | NA | hsa-miR-1 | 15685193 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
