HCSGD entry for ZCCHC11
1. General information
| Official gene symbol | ZCCHC11 |
|---|---|
| Entrez ID | 23318 |
| Gene full name | zinc finger, CCHC domain containing 11 |
| Other gene symbols | PAPD3 TUT4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001816 | Cytokine production | IEA | biological_process |
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA IEA | cellular_component |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0010586 | MiRNA metabolic process | IEA ISS | biological_process |
| GO:0010587 | MiRNA catabolic process | IMP | biological_process |
| GO:0016779 | Nucleotidyltransferase activity | IEA | molecular_function |
| GO:0019827 | Stem cell maintenance | IMP | biological_process |
| GO:0031054 | Pre-miRNA processing | IMP | biological_process |
| GO:0031123 | RNA 3'-end processing | IDA IEA | biological_process |
| GO:0031664 | Regulation of lipopolysaccharide-mediated signaling pathway | IEA | biological_process |
| GO:0032088 | Negative regulation of NF-kappaB transcription factor activity | IEA | biological_process |
| GO:0032755 | Positive regulation of interleukin-6 production | IEA | biological_process |
| GO:0050265 | RNA uridylyltransferase activity | IDA IEA | molecular_function |
| GO:0070102 | Interleukin-6-mediated signaling pathway | IEA | biological_process |
| GO:0071044 | Histone mRNA catabolic process | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7030969644 | 0.1130011094 | 0.9999902473 | 0.6442066710 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2264587690 |
| GSE13712_SHEAR | Down | -0.1625316655 |
| GSE13712_STATIC | Down | -0.0143272525 |
| GSE19018 | Up | 0.2285153685 |
| GSE19899_A1 | Down | -0.3166660734 |
| GSE19899_A2 | Down | -0.5612722617 |
| PubMed_21979375_A1 | Up | 0.2495757976 |
| PubMed_21979375_A2 | Up | 0.2050296808 |
| GSE35957 | Down | -0.3867938818 |
| GSE36640 | Down | -0.2696115734 |
| GSE54402 | Down | -0.0625524650 |
| GSE9593 | Down | -0.3195615499 |
| GSE43922 | Down | -0.1961918832 |
| GSE24585 | Up | 0.3517717891 |
| GSE37065 | Up | 0.0069920303 |
| GSE28863_A1 | Up | 0.5088919607 |
| GSE28863_A2 | Up | 0.6668663817 |
| GSE28863_A3 | Down | -0.4792659473 |
| GSE28863_A4 | Down | -0.3992081194 |
| GSE48662 | Down | -0.0106145461 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-196a-5p | MIMAT0000226 | MIRT048241 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052322 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
