HCSGD entry for POFUT2
1. General information
| Official gene symbol | POFUT2 |
|---|---|
| Entrez ID | 23275 |
| Gene full name | protein O-fucosyltransferase 2 |
| Other gene symbols | C21orf80 FUT13 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001707 | Mesoderm formation | IEA | biological_process |
| GO:0005783 | Endoplasmic reticulum | IEA | cellular_component |
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0006004 | Fucose metabolic process | IEA | biological_process |
| GO:0010468 | Regulation of gene expression | IEA | biological_process |
| GO:0010717 | Regulation of epithelial to mesenchymal transition | IEA | biological_process |
| GO:0036066 | Protein O-linked fucosylation | IDA | biological_process |
| GO:0046922 | Peptide-O-fucosyltransferase activity | IDA | molecular_function |
| GO:0051046 | Regulation of secretion | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3285193496 | 0.8018991452 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2501941935 |
| GSE13712_SHEAR | Up | 0.0526400670 |
| GSE13712_STATIC | Up | 0.0500870885 |
| GSE19018 | Up | 0.1739036442 |
| GSE19899_A1 | Down | -0.0572279012 |
| GSE19899_A2 | Up | 0.2895481870 |
| PubMed_21979375_A1 | Down | -0.5285973538 |
| PubMed_21979375_A2 | Down | -0.1765252023 |
| GSE35957 | Up | 0.0438126174 |
| GSE36640 | Up | 0.4258929173 |
| GSE54402 | Down | -0.1163469442 |
| GSE9593 | Up | 0.0021625902 |
| GSE43922 | Up | 0.0707934804 |
| GSE24585 | Up | 0.1311679872 |
| GSE37065 | Down | -0.1682870760 |
| GSE28863_A1 | Up | 0.3361373448 |
| GSE28863_A2 | Up | 0.4478086586 |
| GSE28863_A3 | Down | -0.0048649935 |
| GSE28863_A4 | Up | 0.0197427801 |
| GSE48662 | Up | 0.5128349291 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018483 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029843 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-454-3p | MIMAT0003885 | MIRT039238 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
