HCSGD entry for DDHD2
1. General information
| Official gene symbol | DDHD2 |
|---|---|
| Entrez ID | 23259 |
| Gene full name | DDHD domain containing 2 |
| Other gene symbols | SAMWD1 SPG54 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005793 | Endoplasmic reticulum-Golgi intermediate compartment | IEA | cellular_component |
| GO:0005794 | Golgi apparatus | IEA | cellular_component |
| GO:0005813 | Centrosome | IDA | cellular_component |
| GO:0005829 | Cytosol | IEA | cellular_component |
| GO:0008219 | Cell death | IEA | biological_process |
| GO:0016042 | Lipid catabolic process | IEA | biological_process |
| GO:0016787 | Hydrolase activity | IEA | molecular_function |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3241715588 | 0.0308925915 | 0.9999902473 | 0.3311875101 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -1.1788211842 |
| GSE13712_SHEAR | Down | -0.1623058672 |
| GSE13712_STATIC | Up | 0.0936311779 |
| GSE19018 | Up | 0.8362609581 |
| GSE19899_A1 | Down | -0.3683231464 |
| GSE19899_A2 | Down | -0.0124523690 |
| PubMed_21979375_A1 | Down | -1.1395104183 |
| PubMed_21979375_A2 | Down | -0.0314799994 |
| GSE35957 | Up | 0.5855483233 |
| GSE36640 | Up | 0.2243734717 |
| GSE54402 | Down | -0.5051428941 |
| GSE9593 | Up | 0.3858765923 |
| GSE43922 | Down | -0.4425194361 |
| GSE24585 | Up | 0.5010967794 |
| GSE37065 | Down | -0.1516877755 |
| GSE28863_A1 | Down | -0.1414043805 |
| GSE28863_A2 | Up | 0.5021098046 |
| GSE28863_A3 | Down | -0.8105378980 |
| GSE28863_A4 | Down | -0.2249384784 |
| GSE48662 | Down | -0.1228181885 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-24-3p | MIMAT0000080 | MIRT030366 | Microarray | Functional MTI (Weak) | 19748357 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030682 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031442 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-99b-5p | MIMAT0000689 | MIRT044196 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10b-5p | MIMAT0000254 | MIRT047446 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
