HCSGD entry for DENND5A
1. General information
| Official gene symbol | DENND5A |
|---|---|
| Entrez ID | 23258 |
| Gene full name | DENN/MADD domain containing 5A |
| Other gene symbols | RAB6IP1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005262 | Calcium channel activity | IBA | molecular_function |
| GO:0005794 | Golgi apparatus | IEA | cellular_component |
| GO:0016020 | Membrane | IBA | cellular_component |
| GO:0017112 | Rab guanyl-nucleotide exchange factor activity | IDA | molecular_function |
| GO:0017137 | Rab GTPase binding | IEA | molecular_function |
| GO:0032313 | Regulation of Rab GTPase activity | IDA | biological_process |
| GO:0032318 | Regulation of Ras GTPase activity | IDA | biological_process |
| GO:0043087 | Regulation of GTPase activity | IDA | biological_process |
| GO:0050982 | Detection of mechanical stimulus | IBA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3643220622 | 0.1240842673 | 0.9999902473 | 0.6773079950 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.4694483430 |
| GSE13712_SHEAR | Down | -0.2665222750 |
| GSE13712_STATIC | Down | -0.2838924908 |
| GSE19018 | Up | 0.0987510428 |
| GSE19899_A1 | Down | -0.8237591628 |
| GSE19899_A2 | Up | 0.0204585126 |
| PubMed_21979375_A1 | Down | -0.3080138761 |
| PubMed_21979375_A2 | Up | 0.2343812126 |
| GSE35957 | Down | -0.2613835703 |
| GSE36640 | Up | 0.1337301672 |
| GSE54402 | Up | 0.1600365531 |
| GSE9593 | Up | 0.2390120080 |
| GSE43922 | Down | -0.3637655958 |
| GSE24585 | Up | 0.4642603275 |
| GSE37065 | Up | 0.2041754540 |
| GSE28863_A1 | Up | 0.5242859139 |
| GSE28863_A2 | Up | 0.4165067313 |
| GSE28863_A3 | Down | -0.7456453586 |
| GSE28863_A4 | Down | -0.0127518556 |
| GSE48662 | Up | 0.3038320960 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-30d-5p | MIMAT0000245 | MIRT047785 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049154 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-25-3p | MIMAT0000081 | MIRT050288 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
