HCSGD entry for PDS5A
1. General information
| Official gene symbol | PDS5A |
|---|---|
| Entrez ID | 23244 |
| Gene full name | PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae) |
| Other gene symbols | SCC-112 SCC112 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000278 | Mitotic cell cycle | TAS | biological_process |
| GO:0000775 | Chromosome, centromeric region | TAS | cellular_component |
| GO:0000785 | Chromatin | IDA | cellular_component |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005694 | Chromosome | TAS | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0007067 | Mitosis | IEA | biological_process |
| GO:0008156 | Negative regulation of DNA replication | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4804363360 | 0.3280470347 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0247379623 |
| GSE13712_SHEAR | Up | 0.2535618291 |
| GSE13712_STATIC | Up | 0.2251315111 |
| GSE19018 | Down | -0.1911539687 |
| GSE19899_A1 | Up | 0.1014199444 |
| GSE19899_A2 | Up | 0.2449572750 |
| PubMed_21979375_A1 | Up | 0.4006603646 |
| PubMed_21979375_A2 | Up | 0.0380039679 |
| GSE35957 | Down | -0.2566172731 |
| GSE36640 | Down | -0.4811050035 |
| GSE54402 | Up | 0.4221514648 |
| GSE9593 | Down | -0.1700484895 |
| GSE43922 | Up | 0.0996859369 |
| GSE24585 | Down | -0.1452063035 |
| GSE37065 | Down | -0.0740008633 |
| GSE28863_A1 | Up | 0.3294865299 |
| GSE28863_A2 | Up | 0.3123084241 |
| GSE28863_A3 | Down | -0.5042445785 |
| GSE28863_A4 | Down | -0.3771189790 |
| GSE48662 | Down | -0.3058135181 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-130b-5p | MIMAT0004680 | MIRT038292 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-93-3p | MIMAT0004509 | MIRT038836 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040257 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-128-3p | MIMAT0000424 | MIRT045888 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-125b-5p | MIMAT0000423 | MIRT045939 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052281 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-129-5p | MIMAT0000242 | NA | hsa-miR-129-5p | 19487295 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
