HCSGD entry for COBL


1. General information

Official gene symbolCOBL
Entrez ID23242
Gene full namecordon-bleu WH2 repeat protein
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000578Embryonic axis specificationIEA ISSbiological_process
GO:0001726RuffleIEA ISScellular_component
GO:0001757Somite specificationIEA ISSbiological_process
GO:0001843Neural tube closureIEA ISSbiological_process
GO:0001889Liver developmentIEA ISSbiological_process
GO:0003779Actin bindingIEAmolecular_function
GO:0003785Actin monomer bindingIEA ISSmolecular_function
GO:0005884Actin filamentIEA ISScellular_component
GO:0005886Plasma membraneIEAcellular_component
GO:0005938Cell cortexIEA ISScellular_component
GO:0016020MembraneIEA ISScellular_component
GO:0030041Actin filament polymerizationIEA ISSbiological_process
GO:0030424AxonISScellular_component
GO:0030425DendriteISScellular_component
GO:0030903Notochord developmentIEA ISSbiological_process
GO:0033504Floor plate developmentIEA ISSbiological_process
GO:0043025Neuronal cell bodyIEA ISScellular_component
GO:0044294Dendritic growth coneIEA ISScellular_component
GO:0044295Axonal growth coneIEA ISScellular_component
GO:0048471Perinuclear region of cytoplasmIEA ISScellular_component
GO:0048565Digestive tract developmentIEA ISSbiological_process
GO:0048669Collateral sprouting in absence of injuryIEA ISSbiological_process
GO:0051639Actin filament network formationIEA ISSbiological_process
GO:1900006Positive regulation of dendrite developmentIEA ISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.57256773300.83072663650.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0911493977
GSE13712_SHEARUp0.1638878535
GSE13712_STATICDown-0.0145172886
GSE19018Up0.1167923077
GSE19899_A1Up0.2102075688
GSE19899_A2Up0.0984788458
PubMed_21979375_A1Up0.0114361534
PubMed_21979375_A2Up0.1293535997
GSE35957Up0.0984328309
GSE36640Up0.1154495231
GSE54402Down-0.0963113146
GSE9593Up0.1017213633
GSE43922Up0.0313125133
GSE24585Down-0.6419628454
GSE37065Down-0.0403089851
GSE28863_A1Down-0.0587548789
GSE28863_A2Up0.0236878945
GSE28863_A3Up0.1848853303
GSE28863_A4Up0.0969959074
GSE48662Down-0.0046329140

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.