HCSGD entry for ARC

1. General information

Official gene symbolARC
Entrez ID23237
Gene full nameactivity-regulated cytoskeleton-associated protein
Other gene symbolsArg3.1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001669Acrosomal vesicleIEAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005768EndosomeIEAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0006897EndocytosisIEAbiological_process
GO:0007010Cytoskeleton organizationIMPbiological_process
GO:0007492Endoderm developmentIEAbiological_process
GO:0007612LearningIEAbiological_process
GO:0009952Anterior/posterior pattern specificationIEAbiological_process
GO:0014069Postsynaptic densityIEAcellular_component
GO:0015629Actin cytoskeletonIEAcellular_component
GO:0016477Cell migrationIMPbiological_process
GO:0022604Regulation of cell morphogenesisIMPbiological_process
GO:0030054Cell junctionIEAcellular_component
GO:0043197Dendritic spineIEAcellular_component
GO:0045211Postsynaptic membraneIEAcellular_component
GO:0048168Regulation of neuronal synaptic plasticityIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.16590686140.92725081490.80571234321.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0606806885
GSE13712_SHEARDown-0.0735999484
GSE13712_STATICUp0.1379675928
GSE19018Up0.2406379945
GSE19899_A1Down-0.0448108026
GSE19899_A2Up0.0441242737
PubMed_21979375_A1Down-0.0023406902
PubMed_21979375_A2Up0.2630657152
GSE35957Down-0.0821004397
GSE36640Up0.0622941120
GSE54402Up0.0608469179
GSE9593Up0.1194754650
GSE43922Up0.1311162915
GSE24585Up0.0349937209
GSE37065Up0.0196056758
GSE28863_A1Down-0.0417763280
GSE28863_A2Up0.1454688908
GSE28863_A3Up0.7783251820
GSE28863_A4Up0.1422115258
GSE48662Down-0.1202522050

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-378a-5pMIMAT0000731MIRT043974CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.