HCSGD entry for RHOBTB2
1. General information
| Official gene symbol | RHOBTB2 |
|---|---|
| Entrez ID | 23221 |
| Gene full name | Rho-related BTB domain containing 2 |
| Other gene symbols | DBC2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005622 | Intracellular | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0007264 | Small GTPase mediated signal transduction | IEA TAS | biological_process |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0051056 | Regulation of small GTPase mediated signal transduction | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8472339501 | 0.3071147981 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1002790167 |
| GSE13712_SHEAR | Up | 0.0093000866 |
| GSE13712_STATIC | Down | -0.0215381625 |
| GSE19018 | Down | -0.0312638257 |
| GSE19899_A1 | Down | -0.0522980730 |
| GSE19899_A2 | Down | -0.5633955076 |
| PubMed_21979375_A1 | Up | 0.5459455647 |
| PubMed_21979375_A2 | Down | -0.1727003532 |
| GSE35957 | Down | -0.1376588681 |
| GSE36640 | Up | 0.0105883194 |
| GSE54402 | Down | -0.1170786244 |
| GSE9593 | Up | 0.1143619766 |
| GSE43922 | Up | 0.0519006772 |
| GSE24585 | Up | 0.1326568080 |
| GSE37065 | Down | -0.1573076790 |
| GSE28863_A1 | Up | 0.0087571766 |
| GSE28863_A2 | Up | 0.4574129845 |
| GSE28863_A3 | Down | -0.2190668143 |
| GSE28863_A4 | Down | -0.2425188513 |
| GSE48662 | Down | -0.0086300067 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-421 | MIMAT0003339 | MIRT039445 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-106b-5p | MIMAT0000680 | MIRT044286 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
