HCSGD entry for JMJD6

1. General information

Official gene symbolJMJD6
Entrez ID23210
Gene full namejumonji domain containing 6
Other gene symbolsPSR PTDSR PTDSR1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001822Kidney developmentIEAbiological_process
GO:0002040Sprouting angiogenesisISSbiological_process
GO:0003723RNA bindingTASmolecular_function
GO:0003727Single-stranded RNA bindingIDAmolecular_function
GO:0004872Receptor activityIEAmolecular_function
GO:0005506Iron ion bindingIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005654NucleoplasmIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005886Plasma membraneIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006355Regulation of transcription, DNA-templatedIEAbiological_process
GO:0006397MRNA processingIEAbiological_process
GO:0007166Cell surface receptor signaling pathwayIEAbiological_process
GO:0007507Heart developmentIEAbiological_process
GO:0008380RNA splicingIEAbiological_process
GO:0018395Peptidyl-lysine hydroxylation to 5-hydroxy-L-lysineIDAbiological_process
GO:0030324Lung developmentIEAbiological_process
GO:0033077T cell differentiation in thymusIEAbiological_process
GO:0033746Histone demethylase activity (H3-R2 specific)IDAmolecular_function
GO:0033749Histone demethylase activity (H4-R3 specific)IDAmolecular_function
GO:0042116Macrophage activationIEAbiological_process
GO:0042802Identical protein bindingIDAmolecular_function
GO:0043654Recognition of apoptotic cellIEAbiological_process
GO:0048024Regulation of mRNA splicing, via spliceosomeIMPbiological_process
GO:0048821Erythrocyte developmentIEAbiological_process
GO:0060041Retina development in camera-type eyeIEAbiological_process
GO:0070078Histone H3-R2 demethylationIDAbiological_process
GO:0070079Histone H4-R3 demethylationIDAbiological_process
GO:0070782Phosphatidylserine exposure on apoptotic cell surfaceIEAbiological_process
GO:0070815Peptidyl-lysine 5-dioxygenase activityIDAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.05894298470.74475315910.52650973871.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.5374376489
GSE13712_SHEARUp0.5867355598
GSE13712_STATICUp0.4697327449
GSE19018Down-0.3438134122
GSE19899_A1Up0.2606129222
GSE19899_A2Up0.4394740330
PubMed_21979375_A1Up1.1309710097
PubMed_21979375_A2Up0.2218330714
GSE35957Up0.0068282595
GSE36640Down-0.1532212154
GSE54402Up0.3599007671
GSE9593Down-0.3982099183
GSE43922Up0.6691428516
GSE24585Up0.1250837407
GSE37065Up0.0694729697
GSE28863_A1Up0.1889338403
GSE28863_A2Up0.1188918125
GSE28863_A3Down-0.1655966820
GSE28863_A4Down-0.0297648500
GSE48662Down-0.3394589515

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-484MIMAT0002174MIRT041794CLASHFunctional MTI (Weak)23622248
hsa-miR-92a-3pMIMAT0000092MIRT049750CLASHFunctional MTI (Weak)23622248
hsa-miR-1260bMIMAT0015041MIRT052729CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

20958309Several receptors were described as "phosphatidylserine receptor: are they all equal
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