HCSGD entry for SEPT6


1. General information

Official gene symbolSEPT6
Entrez ID23157
Gene full nameseptin 6
Other gene symbolsSEP2 SEPT2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000777Condensed chromosome kinetochoreIEAcellular_component
GO:0000910CytokinesisTASbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005525GTP bindingIEA TASmolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005819SpindleIEAcellular_component
GO:0007049Cell cycleIEAbiological_process
GO:0008021Synaptic vesicleIEAcellular_component
GO:0016032Viral processIEAbiological_process
GO:0030496MidbodyIEAcellular_component
GO:0031105Septin complexIEAcellular_component
GO:0032154Cleavage furrowIEAcellular_component
GO:0043679Axon terminusIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.96508160020.01413448580.99999024730.2336706767

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.3781370065
GSE13712_SHEARDown-0.1104688580
GSE13712_STATICUp0.0297165970
GSE19018Down-0.0779472675
GSE19899_A1Down-0.4168766555
GSE19899_A2Down-0.8786486799
PubMed_21979375_A1Down-1.2120675532
PubMed_21979375_A2Down-0.9910276186
GSE35957Down-0.1942497177
GSE36640Down-0.9208802467
GSE54402Down-0.5508080223
GSE9593Down-0.0885964035
GSE43922Down-0.5405457563
GSE24585Up0.3240542153
GSE37065Up0.4541533727
GSE28863_A1Down-0.1912370156
GSE28863_A2Down-0.0392266505
GSE28863_A3Up0.1898645866
GSE28863_A4Down-0.0075975628
GSE48662Down-0.1058546410

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-1MIMAT0000416MIRT023626Proteomics;MicroarrayFunctional MTI (Weak)18668037
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.