HCSGD entry for NFASC

1. General information

Official gene symbolNFASC
Entrez ID23114
Gene full nameneurofascin
Other gene symbolsNF NRCAML
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002175Protein localization to paranode region of axonIEAbiological_process
GO:0005622IntracellularISScellular_component
GO:0005886Plasma membraneIEA TAScellular_component
GO:0007411Axon guidanceIEA TASbiological_process
GO:0007422Peripheral nervous system developmentIEA ISSbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0019226Transmission of nerve impulseIEAbiological_process
GO:0030913Paranodal junction assemblyIEAbiological_process
GO:0033010Paranodal junctionIEAcellular_component
GO:0033268Node of RanvierISS TAScellular_component
GO:0033270Paranode region of axonIEAcellular_component
GO:0042552MyelinationIEA ISSbiological_process
GO:0043194Axon initial segmentISScellular_component
GO:0045162Clustering of voltage-gated sodium channelsIEAbiological_process
GO:0050808Synapse organizationIEAbiological_process
GO:0071205Protein localization to juxtaparanode region of axonIEAbiological_process
GO:0086080Protein binding involved in heterotypic cell-cell adhesionIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.09568066180.87567030510.64740634961.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2106487722
GSE13712_SHEARUp0.0048571532
GSE13712_STATICUp0.0681349981
GSE19018Down-0.3163724320
GSE19899_A1Up0.0054225315
GSE19899_A2Up0.2579377102
PubMed_21979375_A1Up0.1601682475
PubMed_21979375_A2Up0.0825095745
GSE35957Up0.3906872289
GSE36640Up0.2407620989
GSE54402Up0.0907910981
GSE9593Up1.0262993929
GSE43922Up0.1037775474
GSE24585Up0.0920823094
GSE37065Down-0.0785687375
GSE28863_A1Up0.2878302555
GSE28863_A2Up0.3312330562
GSE28863_A3Up0.3177256038
GSE28863_A4Down-0.1370291537
GSE48662Up0.3126617818

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.