HCSGD entry for CDK19
1. General information
| Official gene symbol | CDK19 |
|---|---|
| Entrez ID | 23097 |
| Gene full name | cyclin-dependent kinase 19 |
| Other gene symbols | CDC2L6 CDK11 bA346C16.3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004672 | Protein kinase activity | IEA | molecular_function |
| GO:0004674 | Protein serine/threonine kinase activity | IEA | molecular_function |
| GO:0004693 | Cyclin-dependent protein serine/threonine kinase activity | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0051301 | Cell division | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8163369135 | 0.1217063865 | 0.9999902473 | 0.6700246028 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0756581110 |
| GSE13712_SHEAR | Down | -0.2285116326 |
| GSE13712_STATIC | Down | -0.3657423514 |
| GSE19018 | Up | 0.4102391770 |
| GSE19899_A1 | Down | -0.1637641825 |
| GSE19899_A2 | Down | -0.5185378662 |
| PubMed_21979375_A1 | Down | -0.2582547601 |
| PubMed_21979375_A2 | Down | -0.3129087724 |
| GSE35957 | Down | -0.5932291787 |
| GSE36640 | Down | -0.6955145024 |
| GSE54402 | Up | 0.1621851930 |
| GSE9593 | Up | 0.1988933955 |
| GSE43922 | Down | -0.0152598792 |
| GSE24585 | Up | 0.6509110133 |
| GSE37065 | Up | 0.0934626357 |
| GSE28863_A1 | Up | 0.0629455507 |
| GSE28863_A2 | Up | 0.0698018876 |
| GSE28863_A3 | Down | -0.1811383085 |
| GSE28863_A4 | Down | -0.1616037980 |
| GSE48662 | Down | -0.0079185448 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-373-3p | MIMAT0000726 | MIRT003832 | Microarray | Functional MTI (Weak) | 15685193 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT017357 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-130b-3p | MIMAT0000691 | MIRT020239 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-128-3p | MIMAT0000424 | MIRT021943 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-148a-3p | MIMAT0000243 | MIRT026007 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029199 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030820 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031144 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047678 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-20a-5p | MIMAT0000075 | MIRT050601 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-373-3p | MIMAT0000726 | NA | hsa-miR-373 | 15685193 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
