HCSGD entry for WAPAL

1. General information

Official gene symbolWAPAL
Entrez ID23063
Gene full namewings apart-like homolog (Drosophila)
Other gene symbolsFOE KIAA0261 WAPL
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000278Mitotic cell cycleTASbiological_process
GO:0000775Chromosome, centromeric regionTAScellular_component
GO:0000785ChromatinIDAcellular_component
GO:0000795Synaptonemal complexIEAcellular_component
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005694ChromosomeTAScellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0007067MitosisIEAbiological_process
GO:0008156Negative regulation of DNA replicationIMPbiological_process
GO:0008278Cohesin complexIDAcellular_component
GO:0009636Response to toxic substanceIEAbiological_process
GO:0015630Microtubule cytoskeletonIDAcellular_component
GO:0016032Viral processIEAbiological_process
GO:0035562Negative regulation of chromatin bindingIMPbiological_process
GO:0043231Intracellular membrane-bounded organelleIDAcellular_component
GO:0045875Negative regulation of sister chromatid cohesionIMPbiological_process
GO:0071168Protein localization to chromatinIMPbiological_process
GO:0071922Regulation of cohesin localization to chromatinIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.08811467270.91252705440.62312367011.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1365279511
GSE13712_SHEARDown-0.0058182594
GSE13712_STATICDown-0.1847528325
GSE19018Down-0.1597580558
GSE19899_A1Up0.0576337108
GSE19899_A2Up0.1833374545
PubMed_21979375_A1Up0.6410089998
PubMed_21979375_A2Up0.3847485677
GSE35957Down-0.0374893645
GSE36640Down-0.3888186043
GSE54402Up0.3725360414
GSE9593Down-0.0360228187
GSE43922Up0.0015959057
GSE24585Down-0.0534295019
GSE37065Up0.0229335094
GSE28863_A1Up0.9226646605
GSE28863_A2Up0.8801677377
GSE28863_A3Up0.1371727889
GSE28863_A4Up0.2515059026
GSE48662Down-0.2265288027

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-148a-3pMIMAT0000243MIRT025989SequencingFunctional MTI (Weak)20371350
hsa-miR-193b-3pMIMAT0002819MIRT041566CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.